GABA Analogues and Related Mono‐/Bifunctional Building Blocks Derived from the Fluorocyclobutane Scaffold

A series of GABA analogs and related mono‐ and bifunctional building blocks based on the monofluorinated 1,3‐disubstituted cyclobutane scaffold was designed and synthesized. The synthetic approaches included desilylative deoxyfluorination of TMS‐protected cyanohydrin and iodofluorination of methylen...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	European journal of organic chemistry 2020-08, Vol.2020 (30), p.4755-4767
Hauptverfasser:	Feskov, Illia O., Golub, Bohdan O., Vashchenko, Bohdan V., Levterov, Vadym V., Kondratov, Ivan S., Grygorenko, Oleksandr O., Haufe, Günter
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohols Amino acids Amino alcohols Analogs Cyclobutane Diamines Direct reduction Fluorine Heptanes Hydroxy acids Isomers Scaffolds Stereoselectivity Synthesis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!