Utility of pentachloropyridine in organic synthesis

Pentachloropyridine is one of the most important perhalogenated compounds which find broad applications in many fields of chemistry. This review aims to describe the different strategies developed so far for the synthesis, reaction and use of pentachloropyridine as building blocks in the synthesis o...

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Veröffentlicht in:Journal of the Iranian Chemical Society 2020-09, Vol.17 (9), p.2145-2178
Hauptverfasser: Ranjbar-Karimi, Reza, Davoodian, Tayebeh, Mehrabi, Hossein
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Davoodian, Tayebeh
Mehrabi, Hossein
description Pentachloropyridine is one of the most important perhalogenated compounds which find broad applications in many fields of chemistry. This review aims to describe the different strategies developed so far for the synthesis, reaction and use of pentachloropyridine as building blocks in the synthesis of chemical relevant organic compounds. In the first part of the review, the different synthetic approaches of pentachloropyridine have been described. In the other part, an overview of the utility of pentachloropyridine into heterocyclic compounds, as well as other organic derivatives derived from pentachloropyridine, is presented. It has been shown in the literature that many factors including the nature of nucleophile, reaction condition, and solvent can have significant influences in the regiochemistry of the reactions of this heteroaromatic compound. Graphic abstract
doi_str_mv 10.1007/s13738-020-01909-y
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subjects Analytical Chemistry
Biochemistry
Chemical compounds
Chemical synthesis
Chemistry
Chemistry and Materials Science
Heterocyclic compounds
Inorganic Chemistry
Organic Chemistry
Organic compounds
Physical Chemistry
Review
title Utility of pentachloropyridine in organic synthesis
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