Screening of haplotype for cholesterol deficiency genetic defect in the Russian Holstein cattle population

In our study, we estimated the frequency of haplotype for cholesterol deficiency (HCD) carriers in the Russian Holstein cattle population. We studied 1817 random samples of cows born in 2010-2017 from ten herds and 331 cows and heifers from the other three herds born in 2016-2019, fathers or fathers...

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Veröffentlicht in:Polish journal of veterinary sciences 2020-06, Vol.23 (2), p.313-315
Hauptverfasser: Pozovnikova, M V, Gladyr, E A, Romanenkova, O S, Vasileva, O K, Leibova, V B, Tyshchenko, V I, Dementeva, N V
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container_issue 2
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container_title Polish journal of veterinary sciences
container_volume 23
creator Pozovnikova, M V
Gladyr, E A
Romanenkova, O S
Vasileva, O K
Leibova, V B
Tyshchenko, V I
Dementeva, N V
description In our study, we estimated the frequency of haplotype for cholesterol deficiency (HCD) carriers in the Russian Holstein cattle population. We studied 1817 random samples of cows born in 2010-2017 from ten herds and 331 cows and heifers from the other three herds born in 2016-2019, fathers or fathers of mothers of which were HCD carriers. The method of AS-PCR was used for animals genotyping. In the first group of animals, the incidence of HCD carriers was 8.09%, and in the second one - 23.26%. Our results demonstrated the necessity to test cows for the carriage of the HCD genetic defect in the Russian population of Holstein cattle.
doi_str_mv 10.24425/pjvs.2020.133647
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Animal diseases
Animals
Cattle
Cattle Diseases - genetics
Cholesterol
Cholesterol - deficiency
Genetic Predisposition to Disease
Genetics
Genotyping
Haplotypes
Population studies
title Screening of haplotype for cholesterol deficiency genetic defect in the Russian Holstein cattle population
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