Temperature Dependence of High Frequency Irreversible Electroporation Evaluated in a 3D Tumor Model

Electroporation is a bioelectric phenomenon used to deliver target molecules into cells in vitro and irreversible electroporation (IRE) is an emerging cancer therapy used to treat inoperable tumors in situ . These phenomena are generally considered to be non-thermal in nature. In this study, a 3D tu...

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Veröffentlicht in:	Annals of biomedical engineering 2020-08, Vol.48 (8), p.2233-2246
Hauptverfasser:	Fesmire, Christopher C., Petrella, Ross A., Fogle, Callie A., Gerber, David A., Xing, Lei, Sano, Michael B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Biochemistry Bioelectricity Biological and Medical Physics Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Biophysics Brain cancer Cancer Cell death Cell viability Classical Mechanics Electric fields Electroporation Glioblastoma Glioblastoma cells High frequencies Low temperature Original Article Pancreatic cancer Temperature Temperature dependence Three dimensional models Transfection Tumors
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