10-Hydroxydecanoic Acid Potentially Elicits Antigen-Specific IgA Responses

The effective antigen (Ag) uptake by microfold cells (M-cells) is important for the induction of an efficient mucosal immune responses. Here, we show that 10-hydroxydecanoic acid (10-HDAA) from royal jelly (RJ) potentially supports M-cell differentiation and induces effective antigen-specific mucosa...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biological & pharmaceutical bulletin 2020/08/01, Vol.43(8), pp.1202-1209
Hauptverfasser:	Isayama, Tatsuya, Etoh, Hikaru, Kishimoto, Naoki, Takasaki, Toshimasa, Kuratani, Ayumi, Ikuta, Tomoki, Tatefuji, Tomoki, Takamune, Nobutoki, Muneoka, Atsunobu, Takahashi, Yoshihiro, Misumi, Shogo
Format:	Artikel
Sprache:	eng
Schlagworte:	10-hydroxydecanoic acid Antigens Cell differentiation Epithelium Immune response Immunoglobulin A Intranasal administration Lymphoid tissue microfold cell (M-cell) mucosal immune response Mucosal immunity Nasopharynx NF-κB protein Oral administration Royal jelly
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!