Real-World Eligibility for HIV Pre-exposure Prophylaxis Among People Who Inject Drugs
Recent studies have highlighted the efficacy of and willingness to use pre-exposure prophylaxis (PrEP) to prevent HIV infection among people who inject drugs (PWID), however knowledge of real-world applicability is limited. We aimed to quantify the real-world eligibility for HIV-PrEP among HIV-negat...
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Veröffentlicht in: | AIDS and behavior 2020-08, Vol.24 (8), p.2400-2408 |
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creator | Picard, Jonathan Jacka, Brendan Høj, Stine Laverdière, Émélie Cox, Joseph Roy, Élise Bruneau, Julie |
description | Recent studies have highlighted the efficacy of and willingness to use pre-exposure prophylaxis (PrEP) to prevent HIV infection among people who inject drugs (PWID), however knowledge of real-world applicability is limited. We aimed to quantify the real-world eligibility for HIV-PrEP among HIV-negative PWID in Montreal, Canada (n = 718). Eligibility was calculated according to US Centers for Disease Control and Prevention (CDC) guidelines and compared to risk of HIV acquisition according to the assessing the risk of contracting HIV (ARCH-IDU) risk screening tool. Over one-third of participants (37%) were eligible for HIV PrEP, with 1/3 of these eligible due to sexual risk alone. Half of participants were considered high risk of HIV acquisition according to ARCH-IDU, but there was poor agreement between the two measures. Although a large proportion of PWID were eligible for HIV-PrEP, better tools that are context- and location-informed are needed to identify PWID at higher risk of HIV acquisition. |
doi_str_mv | 10.1007/s10461-020-02800-w |
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We aimed to quantify the real-world eligibility for HIV-PrEP among HIV-negative PWID in Montreal, Canada (n = 718). Eligibility was calculated according to US Centers for Disease Control and Prevention (CDC) guidelines and compared to risk of HIV acquisition according to the assessing the risk of contracting HIV (ARCH-IDU) risk screening tool. Over one-third of participants (37%) were eligible for HIV PrEP, with 1/3 of these eligible due to sexual risk alone. Half of participants were considered high risk of HIV acquisition according to ARCH-IDU, but there was poor agreement between the two measures. Although a large proportion of PWID were eligible for HIV-PrEP, better tools that are context- and location-informed are needed to identify PWID at higher risk of HIV acquisition.</description><identifier>ISSN: 1090-7165</identifier><identifier>EISSN: 1573-3254</identifier><identifier>DOI: 10.1007/s10461-020-02800-w</identifier><identifier>PMID: 31997057</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Anti-HIV Agents - therapeutic use ; Arches ; Canada - epidemiology ; Condoms ; Disease control ; Disease prevention ; Drug use ; Drugs ; Gays & lesbians ; Health Psychology ; HIV ; HIV Infections - drug therapy ; HIV Infections - epidemiology ; HIV Infections - prevention & control ; Human immunodeficiency virus ; Humans ; Infectious Diseases ; Medicine ; Medicine & Public Health ; Mens health ; Original Paper ; Pre-Exposure Prophylaxis ; Prophylaxis ; Public Health ; Risk ; Risk assessment ; Sexually transmitted diseases ; STD ; Substance Abuse, Intravenous - drug therapy ; Substance Abuse, Intravenous - epidemiology ; Tests</subject><ispartof>AIDS and behavior, 2020-08, Vol.24 (8), p.2400-2408</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020</rights><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-9744a77d567f591d49d7e17eb56c76048b9fb8511a070c6c3065b14e0cf177743</citedby><cites>FETCH-LOGICAL-c375t-9744a77d567f591d49d7e17eb56c76048b9fb8511a070c6c3065b14e0cf177743</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10461-020-02800-w$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10461-020-02800-w$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27321,27901,27902,33751,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31997057$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Picard, Jonathan</creatorcontrib><creatorcontrib>Jacka, Brendan</creatorcontrib><creatorcontrib>Høj, Stine</creatorcontrib><creatorcontrib>Laverdière, Émélie</creatorcontrib><creatorcontrib>Cox, Joseph</creatorcontrib><creatorcontrib>Roy, Élise</creatorcontrib><creatorcontrib>Bruneau, Julie</creatorcontrib><title>Real-World Eligibility for HIV Pre-exposure Prophylaxis Among People Who Inject Drugs</title><title>AIDS and behavior</title><addtitle>AIDS Behav</addtitle><addtitle>AIDS Behav</addtitle><description>Recent studies have highlighted the efficacy of and willingness to use pre-exposure prophylaxis (PrEP) to prevent HIV infection among people who inject drugs (PWID), however knowledge of real-world applicability is limited. We aimed to quantify the real-world eligibility for HIV-PrEP among HIV-negative PWID in Montreal, Canada (n = 718). Eligibility was calculated according to US Centers for Disease Control and Prevention (CDC) guidelines and compared to risk of HIV acquisition according to the assessing the risk of contracting HIV (ARCH-IDU) risk screening tool. Over one-third of participants (37%) were eligible for HIV PrEP, with 1/3 of these eligible due to sexual risk alone. Half of participants were considered high risk of HIV acquisition according to ARCH-IDU, but there was poor agreement between the two measures. Although a large proportion of PWID were eligible for HIV-PrEP, better tools that are context- and location-informed are needed to identify PWID at higher risk of HIV acquisition.</description><subject>Anti-HIV Agents - therapeutic use</subject><subject>Arches</subject><subject>Canada - epidemiology</subject><subject>Condoms</subject><subject>Disease control</subject><subject>Disease prevention</subject><subject>Drug use</subject><subject>Drugs</subject><subject>Gays & lesbians</subject><subject>Health Psychology</subject><subject>HIV</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - epidemiology</subject><subject>HIV Infections - prevention & control</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Infectious Diseases</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mens health</subject><subject>Original Paper</subject><subject>Pre-Exposure 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infection among people who inject drugs (PWID), however knowledge of real-world applicability is limited. We aimed to quantify the real-world eligibility for HIV-PrEP among HIV-negative PWID in Montreal, Canada (n = 718). Eligibility was calculated according to US Centers for Disease Control and Prevention (CDC) guidelines and compared to risk of HIV acquisition according to the assessing the risk of contracting HIV (ARCH-IDU) risk screening tool. Over one-third of participants (37%) were eligible for HIV PrEP, with 1/3 of these eligible due to sexual risk alone. Half of participants were considered high risk of HIV acquisition according to ARCH-IDU, but there was poor agreement between the two measures. Although a large proportion of PWID were eligible for HIV-PrEP, better tools that are context- and location-informed are needed to identify PWID at higher risk of HIV acquisition.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>31997057</pmid><doi>10.1007/s10461-020-02800-w</doi><tpages>9</tpages></addata></record> |
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subjects | Anti-HIV Agents - therapeutic use Arches Canada - epidemiology Condoms Disease control Disease prevention Drug use Drugs Gays & lesbians Health Psychology HIV HIV Infections - drug therapy HIV Infections - epidemiology HIV Infections - prevention & control Human immunodeficiency virus Humans Infectious Diseases Medicine Medicine & Public Health Mens health Original Paper Pre-Exposure Prophylaxis Prophylaxis Public Health Risk Risk assessment Sexually transmitted diseases STD Substance Abuse, Intravenous - drug therapy Substance Abuse, Intravenous - epidemiology Tests |
title | Real-World Eligibility for HIV Pre-exposure Prophylaxis Among People Who Inject Drugs |
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