Nephrotic syndrome and pulmonary hypertension as complications of intravenous drug abuse
This case report discusses a patient with nephrotic syndrome, pulmonary hypertension, and repeated episodes of infections. He had a history of intravenous drug abuse. Kidney biopsy revealed the rare finding of numerous foam cells, mainly in glomeruli. The solvent used for the drugs is thought to be...
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| Veröffentlicht in: | APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2020-08, Vol.128 (8), p.506-510 |
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| container_title | APMIS : acta pathologica, microbiologica et immunologica Scandinavica |
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| creator | Mohan, Janany Nybø, Camilla J. Vegsundvåg, Johnny Roald, Borghild Liem, Ylian S. |
| description | This case report discusses a patient with nephrotic syndrome, pulmonary hypertension, and repeated episodes of infections. He had a history of intravenous drug abuse. Kidney biopsy revealed the rare finding of numerous foam cells, mainly in glomeruli. The solvent used for the drugs is thought to be responsible for the foam cells. In line with previous reports, we suspect that the pulmonary hypertension is consistent with foam cells in pulmonary capillaries or fat embolism syndrome due to the intravenous administered drugs. Our case demonstrates that the use of intravenous drugs can lead to widely varying symptoms. Globally, the prevalence of substance abuse is increasing. Knowledge about their damaging effects is crucial in both clinical practice and anatomic pathology. |
| doi_str_mv | 10.1111/apm.13065 |
| format | Article |
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He had a history of intravenous drug abuse. Kidney biopsy revealed the rare finding of numerous foam cells, mainly in glomeruli. The solvent used for the drugs is thought to be responsible for the foam cells. In line with previous reports, we suspect that the pulmonary hypertension is consistent with foam cells in pulmonary capillaries or fat embolism syndrome due to the intravenous administered drugs. Our case demonstrates that the use of intravenous drugs can lead to widely varying symptoms. Globally, the prevalence of substance abuse is increasing. Knowledge about their damaging effects is crucial in both clinical practice and anatomic pathology.</description><identifier>ISSN: 0903-4641</identifier><identifier>EISSN: 1600-0463</identifier><identifier>DOI: 10.1111/apm.13065</identifier><language>eng</language><publisher>Copenhagen: Wiley Subscription Services, Inc</publisher><subject>Bacteriology ; Biopsy ; Capillaries ; Complications ; designer drugs ; Drug abuse ; Drug solvents ; Drugs ; Embolism ; histopathology ; Hypertension ; Intravenous administration ; Kidney diseases ; nephrology ; Nephrotic syndrome ; patholgy ; Pulmonary hypertension</subject><ispartof>APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2020-08, Vol.128 (8), p.506-510</ispartof><rights>2020 Scandinavian Societies for Medical Microbiology and Pathology. 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He had a history of intravenous drug abuse. Kidney biopsy revealed the rare finding of numerous foam cells, mainly in glomeruli. The solvent used for the drugs is thought to be responsible for the foam cells. In line with previous reports, we suspect that the pulmonary hypertension is consistent with foam cells in pulmonary capillaries or fat embolism syndrome due to the intravenous administered drugs. Our case demonstrates that the use of intravenous drugs can lead to widely varying symptoms. Globally, the prevalence of substance abuse is increasing. Knowledge about their damaging effects is crucial in both clinical practice and anatomic pathology.</description><subject>Bacteriology</subject><subject>Biopsy</subject><subject>Capillaries</subject><subject>Complications</subject><subject>designer drugs</subject><subject>Drug abuse</subject><subject>Drug solvents</subject><subject>Drugs</subject><subject>Embolism</subject><subject>histopathology</subject><subject>Hypertension</subject><subject>Intravenous administration</subject><subject>Kidney diseases</subject><subject>nephrology</subject><subject>Nephrotic syndrome</subject><subject>patholgy</subject><subject>Pulmonary hypertension</subject><issn>0903-4641</issn><issn>1600-0463</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp1kDtPwzAQgC0EEqUw8A8sMTGk9SuOM1YVFKTyGEBis1zHoakS29gJKP8eQ1i55XS67-50HwCXGC1wiqXy3QJTxPMjMMMcoQwxTo_BDJWIZowzfArOYjwghIngxQy8PRq_D65vNIyjrYLrDFS2gn5oO2dVGOF-9Cb0xsbGWagi1K7zbaNVn-oIXQ0b2wf1aawbIqzC8A7VbojmHJzUqo3m4i_Pwevtzcv6Lts-be7Xq22mKS_yrC5prSkWKNdclSwvFRaMlDvNBDGCMc2ZELrSGNO8FogWmqQGwwVVXFWU0zm4mvb64D4GE3t5cEOw6aQkjBSsxAXJE3U9UTq4GIOppQ9Nl96TGMkfcTKJk7_iEruc2K-mNeP_oFw9P0wT3yWTb54</recordid><startdate>202008</startdate><enddate>202008</enddate><creator>Mohan, Janany</creator><creator>Nybø, Camilla J.</creator><creator>Vegsundvåg, Johnny</creator><creator>Roald, Borghild</creator><creator>Liem, Ylian S.</creator><general>Wiley Subscription Services, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T5</scope><scope>7T7</scope><scope>7TO</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope></search><sort><creationdate>202008</creationdate><title>Nephrotic syndrome and pulmonary hypertension as complications of intravenous drug abuse</title><author>Mohan, Janany ; Nybø, Camilla J. ; Vegsundvåg, Johnny ; Roald, Borghild ; Liem, Ylian S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3675-f93fc31805c6a9459a18429bc482e844c6488cdc1135f8037c282e4173a6ad363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Bacteriology</topic><topic>Biopsy</topic><topic>Capillaries</topic><topic>Complications</topic><topic>designer drugs</topic><topic>Drug abuse</topic><topic>Drug solvents</topic><topic>Drugs</topic><topic>Embolism</topic><topic>histopathology</topic><topic>Hypertension</topic><topic>Intravenous administration</topic><topic>Kidney diseases</topic><topic>nephrology</topic><topic>Nephrotic syndrome</topic><topic>patholgy</topic><topic>Pulmonary hypertension</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mohan, Janany</creatorcontrib><creatorcontrib>Nybø, Camilla J.</creatorcontrib><creatorcontrib>Vegsundvåg, Johnny</creatorcontrib><creatorcontrib>Roald, Borghild</creatorcontrib><creatorcontrib>Liem, Ylian S.</creatorcontrib><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>APMIS : acta pathologica, microbiologica et immunologica Scandinavica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mohan, Janany</au><au>Nybø, Camilla J.</au><au>Vegsundvåg, Johnny</au><au>Roald, Borghild</au><au>Liem, Ylian S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nephrotic syndrome and pulmonary hypertension as complications of intravenous drug abuse</atitle><jtitle>APMIS : acta pathologica, microbiologica et immunologica Scandinavica</jtitle><date>2020-08</date><risdate>2020</risdate><volume>128</volume><issue>8</issue><spage>506</spage><epage>510</epage><pages>506-510</pages><issn>0903-4641</issn><eissn>1600-0463</eissn><abstract>This case report discusses a patient with nephrotic syndrome, pulmonary hypertension, and repeated episodes of infections. 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| subjects | Bacteriology Biopsy Capillaries Complications designer drugs Drug abuse Drug solvents Drugs Embolism histopathology Hypertension Intravenous administration Kidney diseases nephrology Nephrotic syndrome patholgy Pulmonary hypertension |
| title | Nephrotic syndrome and pulmonary hypertension as complications of intravenous drug abuse |
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