Cutaneous pleomorphic fibromas arising in patients with germline TP53 mutations

Pleomorphic fibromas are rare benign cutaneous neoplasms associated with deletion/loss of chromosomes 13q and 17p, where RB1 and TP53 are located, respectively. Herein, we report five cases of pleomorphic fibroma arising in patients with germline TP53 mutations, suggesting a potential link with Li‐F...

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Veröffentlicht in:	Journal of cutaneous pathology 2020-08, Vol.47 (8), p.734-741
Hauptverfasser:	Cloutier, Jeffrey M., Shalin, Sara C., Lindberg, Matthew, Gardner, Jerad M., Fernandez‐Pol, Sebastian, Zaba, Lisa, Novoa, Roberto, Brown, Ryanne A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosome deletion Gene deletion Li‐Fraumeni syndrome Mutation p53 p53 Protein pleomorphic fibroma Stellate cells Tumor cells Tumors
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