Coffee consumption and risk of colorectal cancer in the Cancer Prevention Study-II Nutrition Cohort
•Decaffeinated, but not caffeinated, coffee was associated with lower CRC risk.•Risk associated with caffeinated coffee varied by subsite.•Additional research should confirm subsite-specific findings observed herein. The association between coffee consumption and colorectal cancer risk generally app...
Gespeichert in:
| Veröffentlicht in: | Cancer epidemiology 2020-08, Vol.67, p.101730, Article 101730 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | 101730 |
| container_title | Cancer epidemiology |
| container_volume | 67 |
| creator | Um, Caroline Y. McCullough, Marjorie L. Guinter, Mark A. Campbell, Peter T. Jacobs, Eric J. Gapstur, Susan M. |
| description | •Decaffeinated, but not caffeinated, coffee was associated with lower CRC risk.•Risk associated with caffeinated coffee varied by subsite.•Additional research should confirm subsite-specific findings observed herein.
The association between coffee consumption and colorectal cancer risk generally appears null, but recent evidence suggests that risk may vary by coffee type. We examined associations of caffeinated and decaffeinated coffee intake with colorectal cancer risk overall and with colon and rectum separately, among older U.S. men and women.
In 1999, 47,010 men and 60,051 women with no previous diagnosis of cancer, aged 47–96 years, in the Cancer Prevention Study-II Nutrition Cohort completed a food frequency questionnaire that assessed caffeinated and decaffeinated coffee intake; consumption was updated in 2003. A total of 1829 colorectal cancer cases were verified through June 2015. Cox proportional hazards regression was used to estimate multivariable-adjusted hazard rate ratios (HRs) and 95% confidence intervals (CIs), adjusting for smoking history, alcohol, caffeinated/decaffeinated coffee intake (depending on the model), and other colorectal cancer risk factors.
Consumption of ≥2 cups/day of decaffeinated coffee, compared to no decaffeinated coffee, was associated with lower risk of overall colorectal cancer (HR = 0.82, 95% CI: 0.69−0.96, P-trend = 0.04), colon cancer (HR = 0.82, 95% CI: 0.69−0.99, P-trend = 0.05) and rectal cancer (HR = 0.63, 95% CI: 0.40−0.99, P-trend = 0.17). Consumption of ≥2 cups/day of caffeinated coffee was associated with higher risk of rectal cancer (HR = 1.37, 95% CI: 0.99–1.89, P-trend = 0.04), but not with colorectal or colon cancer.
In this prospective study, higher intake of decaffeinated coffee was associated with lower risk of colorectal, colon, and rectal cancers. Further study on associations of caffeinated and decaffeinated coffee with colorectal cancer risk by subsite is needed. |
| doi_str_mv | 10.1016/j.canep.2020.101730 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2425586610</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1877782120300643</els_id><sourcerecordid>2425586610</sourcerecordid><originalsourceid>FETCH-LOGICAL-c387t-a43182131f0e3b6ece8eff8d1e633921cad548b3537ed6900b27440c92a7bfb43</originalsourceid><addsrcrecordid>eNp9kEtLAzEUhYMotlZ_gSAB11PzmFcXLmTwUSgqqOAuzGRuaMZ2UpNMof_edKa6dJXkcM49uR9Cl5RMKaHpTTOVZQubKSOsVzJOjtCY5lkWZTn_PP67MzpCZ841hKQppckpGnGWsDSN4zGShVEKAEvTum698dq0uGxrbLX7wkYFfWUsSF-ucGiTYLFusV8CLobXq4UttH3szXf1LprP8XPnre6lwiyN9efoRJUrBxeHc4I-Hu7fi6do8fI4L-4WkeR55qMy5jT8lVNFgFcpSMhBqbymkHI-Y1SWdRLnFU94BnU6I6RiWRwTOWNlVqkq5hN0PczdWPPdgfOiMZ1tQ6VgMUuSPKxPgosPLmmNcxaU2Fi9Lu1OUCL2YEUjerBiD1YMYEPq6jC7q9ZQ_2V-SQbD7WCAsOFWgxVOagiMar3nJ2qj_y34Adawijs</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2425586610</pqid></control><display><type>article</type><title>Coffee consumption and risk of colorectal cancer in the Cancer Prevention Study-II Nutrition Cohort</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Um, Caroline Y. ; McCullough, Marjorie L. ; Guinter, Mark A. ; Campbell, Peter T. ; Jacobs, Eric J. ; Gapstur, Susan M.</creator><creatorcontrib>Um, Caroline Y. ; McCullough, Marjorie L. ; Guinter, Mark A. ; Campbell, Peter T. ; Jacobs, Eric J. ; Gapstur, Susan M.</creatorcontrib><description>•Decaffeinated, but not caffeinated, coffee was associated with lower CRC risk.•Risk associated with caffeinated coffee varied by subsite.•Additional research should confirm subsite-specific findings observed herein.
The association between coffee consumption and colorectal cancer risk generally appears null, but recent evidence suggests that risk may vary by coffee type. We examined associations of caffeinated and decaffeinated coffee intake with colorectal cancer risk overall and with colon and rectum separately, among older U.S. men and women.
In 1999, 47,010 men and 60,051 women with no previous diagnosis of cancer, aged 47–96 years, in the Cancer Prevention Study-II Nutrition Cohort completed a food frequency questionnaire that assessed caffeinated and decaffeinated coffee intake; consumption was updated in 2003. A total of 1829 colorectal cancer cases were verified through June 2015. Cox proportional hazards regression was used to estimate multivariable-adjusted hazard rate ratios (HRs) and 95% confidence intervals (CIs), adjusting for smoking history, alcohol, caffeinated/decaffeinated coffee intake (depending on the model), and other colorectal cancer risk factors.
Consumption of ≥2 cups/day of decaffeinated coffee, compared to no decaffeinated coffee, was associated with lower risk of overall colorectal cancer (HR = 0.82, 95% CI: 0.69−0.96, P-trend = 0.04), colon cancer (HR = 0.82, 95% CI: 0.69−0.99, P-trend = 0.05) and rectal cancer (HR = 0.63, 95% CI: 0.40−0.99, P-trend = 0.17). Consumption of ≥2 cups/day of caffeinated coffee was associated with higher risk of rectal cancer (HR = 1.37, 95% CI: 0.99–1.89, P-trend = 0.04), but not with colorectal or colon cancer.
In this prospective study, higher intake of decaffeinated coffee was associated with lower risk of colorectal, colon, and rectal cancers. Further study on associations of caffeinated and decaffeinated coffee with colorectal cancer risk by subsite is needed.</description><identifier>ISSN: 1877-7821</identifier><identifier>EISSN: 1877-783X</identifier><identifier>DOI: 10.1016/j.canep.2020.101730</identifier><identifier>PMID: 32526644</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Aged ; Caffeine ; Caffeine - administration & dosage ; Caffeine - adverse effects ; Cancer ; Coffee ; Coffee - adverse effects ; Cohort analysis ; Cohort study ; Colon ; Colon cancer ; Colorectal cancer ; Colorectal carcinoma ; Colorectal Neoplasms - etiology ; Colorectal Neoplasms - prevention & control ; Colorectal subsite ; Confidence intervals ; Cups ; Disease prevention ; Epidemiology ; Female ; Health risk assessment ; Health risks ; Hormone replacement therapy ; Humans ; Male ; Medical research ; Mortality ; Nonsteroidal anti-inflammatory drugs ; Nutrition ; Nutrition research ; Prevention ; Prognosis ; Prospective Studies ; Questionnaires ; Rectum ; Risk analysis ; Risk Factors ; Smoking ; Statistical analysis ; Surveys and Questionnaires ; Womens health</subject><ispartof>Cancer epidemiology, 2020-08, Vol.67, p.101730, Article 101730</ispartof><rights>2020 Elsevier Ltd</rights><rights>Copyright © 2020 Elsevier Ltd. All rights reserved.</rights><rights>2020. Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-a43182131f0e3b6ece8eff8d1e633921cad548b3537ed6900b27440c92a7bfb43</citedby><cites>FETCH-LOGICAL-c387t-a43182131f0e3b6ece8eff8d1e633921cad548b3537ed6900b27440c92a7bfb43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1877782120300643$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32526644$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Um, Caroline Y.</creatorcontrib><creatorcontrib>McCullough, Marjorie L.</creatorcontrib><creatorcontrib>Guinter, Mark A.</creatorcontrib><creatorcontrib>Campbell, Peter T.</creatorcontrib><creatorcontrib>Jacobs, Eric J.</creatorcontrib><creatorcontrib>Gapstur, Susan M.</creatorcontrib><title>Coffee consumption and risk of colorectal cancer in the Cancer Prevention Study-II Nutrition Cohort</title><title>Cancer epidemiology</title><addtitle>Cancer Epidemiol</addtitle><description>•Decaffeinated, but not caffeinated, coffee was associated with lower CRC risk.•Risk associated with caffeinated coffee varied by subsite.•Additional research should confirm subsite-specific findings observed herein.
The association between coffee consumption and colorectal cancer risk generally appears null, but recent evidence suggests that risk may vary by coffee type. We examined associations of caffeinated and decaffeinated coffee intake with colorectal cancer risk overall and with colon and rectum separately, among older U.S. men and women.
In 1999, 47,010 men and 60,051 women with no previous diagnosis of cancer, aged 47–96 years, in the Cancer Prevention Study-II Nutrition Cohort completed a food frequency questionnaire that assessed caffeinated and decaffeinated coffee intake; consumption was updated in 2003. A total of 1829 colorectal cancer cases were verified through June 2015. Cox proportional hazards regression was used to estimate multivariable-adjusted hazard rate ratios (HRs) and 95% confidence intervals (CIs), adjusting for smoking history, alcohol, caffeinated/decaffeinated coffee intake (depending on the model), and other colorectal cancer risk factors.
Consumption of ≥2 cups/day of decaffeinated coffee, compared to no decaffeinated coffee, was associated with lower risk of overall colorectal cancer (HR = 0.82, 95% CI: 0.69−0.96, P-trend = 0.04), colon cancer (HR = 0.82, 95% CI: 0.69−0.99, P-trend = 0.05) and rectal cancer (HR = 0.63, 95% CI: 0.40−0.99, P-trend = 0.17). Consumption of ≥2 cups/day of caffeinated coffee was associated with higher risk of rectal cancer (HR = 1.37, 95% CI: 0.99–1.89, P-trend = 0.04), but not with colorectal or colon cancer.
In this prospective study, higher intake of decaffeinated coffee was associated with lower risk of colorectal, colon, and rectal cancers. Further study on associations of caffeinated and decaffeinated coffee with colorectal cancer risk by subsite is needed.</description><subject>Aged</subject><subject>Caffeine</subject><subject>Caffeine - administration & dosage</subject><subject>Caffeine - adverse effects</subject><subject>Cancer</subject><subject>Coffee</subject><subject>Coffee - adverse effects</subject><subject>Cohort analysis</subject><subject>Cohort study</subject><subject>Colon</subject><subject>Colon cancer</subject><subject>Colorectal cancer</subject><subject>Colorectal carcinoma</subject><subject>Colorectal Neoplasms - etiology</subject><subject>Colorectal Neoplasms - prevention & control</subject><subject>Colorectal subsite</subject><subject>Confidence intervals</subject><subject>Cups</subject><subject>Disease prevention</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Health risk assessment</subject><subject>Health risks</subject><subject>Hormone replacement therapy</subject><subject>Humans</subject><subject>Male</subject><subject>Medical research</subject><subject>Mortality</subject><subject>Nonsteroidal anti-inflammatory drugs</subject><subject>Nutrition</subject><subject>Nutrition research</subject><subject>Prevention</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Questionnaires</subject><subject>Rectum</subject><subject>Risk analysis</subject><subject>Risk Factors</subject><subject>Smoking</subject><subject>Statistical analysis</subject><subject>Surveys and Questionnaires</subject><subject>Womens health</subject><issn>1877-7821</issn><issn>1877-783X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kEtLAzEUhYMotlZ_gSAB11PzmFcXLmTwUSgqqOAuzGRuaMZ2UpNMof_edKa6dJXkcM49uR9Cl5RMKaHpTTOVZQubKSOsVzJOjtCY5lkWZTn_PP67MzpCZ841hKQppckpGnGWsDSN4zGShVEKAEvTum698dq0uGxrbLX7wkYFfWUsSF-ucGiTYLFusV8CLobXq4UttH3szXf1LprP8XPnre6lwiyN9efoRJUrBxeHc4I-Hu7fi6do8fI4L-4WkeR55qMy5jT8lVNFgFcpSMhBqbymkHI-Y1SWdRLnFU94BnU6I6RiWRwTOWNlVqkq5hN0PczdWPPdgfOiMZ1tQ6VgMUuSPKxPgosPLmmNcxaU2Fi9Lu1OUCL2YEUjerBiD1YMYEPq6jC7q9ZQ_2V-SQbD7WCAsOFWgxVOagiMar3nJ2qj_y34Adawijs</recordid><startdate>202008</startdate><enddate>202008</enddate><creator>Um, Caroline Y.</creator><creator>McCullough, Marjorie L.</creator><creator>Guinter, Mark A.</creator><creator>Campbell, Peter T.</creator><creator>Jacobs, Eric J.</creator><creator>Gapstur, Susan M.</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>202008</creationdate><title>Coffee consumption and risk of colorectal cancer in the Cancer Prevention Study-II Nutrition Cohort</title><author>Um, Caroline Y. ; McCullough, Marjorie L. ; Guinter, Mark A. ; Campbell, Peter T. ; Jacobs, Eric J. ; Gapstur, Susan M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-a43182131f0e3b6ece8eff8d1e633921cad548b3537ed6900b27440c92a7bfb43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aged</topic><topic>Caffeine</topic><topic>Caffeine - administration & dosage</topic><topic>Caffeine - adverse effects</topic><topic>Cancer</topic><topic>Coffee</topic><topic>Coffee - adverse effects</topic><topic>Cohort analysis</topic><topic>Cohort study</topic><topic>Colon</topic><topic>Colon cancer</topic><topic>Colorectal cancer</topic><topic>Colorectal carcinoma</topic><topic>Colorectal Neoplasms - etiology</topic><topic>Colorectal Neoplasms - prevention & control</topic><topic>Colorectal subsite</topic><topic>Confidence intervals</topic><topic>Cups</topic><topic>Disease prevention</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Health risk assessment</topic><topic>Health risks</topic><topic>Hormone replacement therapy</topic><topic>Humans</topic><topic>Male</topic><topic>Medical research</topic><topic>Mortality</topic><topic>Nonsteroidal anti-inflammatory drugs</topic><topic>Nutrition</topic><topic>Nutrition research</topic><topic>Prevention</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Questionnaires</topic><topic>Rectum</topic><topic>Risk analysis</topic><topic>Risk Factors</topic><topic>Smoking</topic><topic>Statistical analysis</topic><topic>Surveys and Questionnaires</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Um, Caroline Y.</creatorcontrib><creatorcontrib>McCullough, Marjorie L.</creatorcontrib><creatorcontrib>Guinter, Mark A.</creatorcontrib><creatorcontrib>Campbell, Peter T.</creatorcontrib><creatorcontrib>Jacobs, Eric J.</creatorcontrib><creatorcontrib>Gapstur, Susan M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>Cancer epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Um, Caroline Y.</au><au>McCullough, Marjorie L.</au><au>Guinter, Mark A.</au><au>Campbell, Peter T.</au><au>Jacobs, Eric J.</au><au>Gapstur, Susan M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coffee consumption and risk of colorectal cancer in the Cancer Prevention Study-II Nutrition Cohort</atitle><jtitle>Cancer epidemiology</jtitle><addtitle>Cancer Epidemiol</addtitle><date>2020-08</date><risdate>2020</risdate><volume>67</volume><spage>101730</spage><pages>101730-</pages><artnum>101730</artnum><issn>1877-7821</issn><eissn>1877-783X</eissn><abstract>•Decaffeinated, but not caffeinated, coffee was associated with lower CRC risk.•Risk associated with caffeinated coffee varied by subsite.•Additional research should confirm subsite-specific findings observed herein.
The association between coffee consumption and colorectal cancer risk generally appears null, but recent evidence suggests that risk may vary by coffee type. We examined associations of caffeinated and decaffeinated coffee intake with colorectal cancer risk overall and with colon and rectum separately, among older U.S. men and women.
In 1999, 47,010 men and 60,051 women with no previous diagnosis of cancer, aged 47–96 years, in the Cancer Prevention Study-II Nutrition Cohort completed a food frequency questionnaire that assessed caffeinated and decaffeinated coffee intake; consumption was updated in 2003. A total of 1829 colorectal cancer cases were verified through June 2015. Cox proportional hazards regression was used to estimate multivariable-adjusted hazard rate ratios (HRs) and 95% confidence intervals (CIs), adjusting for smoking history, alcohol, caffeinated/decaffeinated coffee intake (depending on the model), and other colorectal cancer risk factors.
Consumption of ≥2 cups/day of decaffeinated coffee, compared to no decaffeinated coffee, was associated with lower risk of overall colorectal cancer (HR = 0.82, 95% CI: 0.69−0.96, P-trend = 0.04), colon cancer (HR = 0.82, 95% CI: 0.69−0.99, P-trend = 0.05) and rectal cancer (HR = 0.63, 95% CI: 0.40−0.99, P-trend = 0.17). Consumption of ≥2 cups/day of caffeinated coffee was associated with higher risk of rectal cancer (HR = 1.37, 95% CI: 0.99–1.89, P-trend = 0.04), but not with colorectal or colon cancer.
In this prospective study, higher intake of decaffeinated coffee was associated with lower risk of colorectal, colon, and rectal cancers. Further study on associations of caffeinated and decaffeinated coffee with colorectal cancer risk by subsite is needed.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>32526644</pmid><doi>10.1016/j.canep.2020.101730</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1877-7821 |
| ispartof | Cancer epidemiology, 2020-08, Vol.67, p.101730, Article 101730 |
| issn | 1877-7821 1877-783X |
| language | eng |
| recordid | cdi_proquest_journals_2425586610 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Aged Caffeine Caffeine - administration & dosage Caffeine - adverse effects Cancer Coffee Coffee - adverse effects Cohort analysis Cohort study Colon Colon cancer Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - etiology Colorectal Neoplasms - prevention & control Colorectal subsite Confidence intervals Cups Disease prevention Epidemiology Female Health risk assessment Health risks Hormone replacement therapy Humans Male Medical research Mortality Nonsteroidal anti-inflammatory drugs Nutrition Nutrition research Prevention Prognosis Prospective Studies Questionnaires Rectum Risk analysis Risk Factors Smoking Statistical analysis Surveys and Questionnaires Womens health |
| title | Coffee consumption and risk of colorectal cancer in the Cancer Prevention Study-II Nutrition Cohort |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-20T20%3A44%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Coffee%20consumption%20and%20risk%20of%20colorectal%20cancer%20in%20the%20Cancer%20Prevention%20Study-II%20Nutrition%20Cohort&rft.jtitle=Cancer%20epidemiology&rft.au=Um,%20Caroline%20Y.&rft.date=2020-08&rft.volume=67&rft.spage=101730&rft.pages=101730-&rft.artnum=101730&rft.issn=1877-7821&rft.eissn=1877-783X&rft_id=info:doi/10.1016/j.canep.2020.101730&rft_dat=%3Cproquest_cross%3E2425586610%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2425586610&rft_id=info:pmid/32526644&rft_els_id=S1877782120300643&rfr_iscdi=true |