A five-gene signature derived from m6A regulators to improve prognosis prediction of neuroblastoma

N6-methyladenosine (m6a) is the most abundant form of methylated modification in eukaryotic mRNA. However, the role of m6A-related genes in neuroblastoma (NB), one of the most common paediatric malignant tumours, is not well known. This study aimed to determine the prognostic role of m6A-related gen...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer biomarkers : section A of Disease markers 2020-01, Vol.28 (3), p.275-284
Hauptverfasser:	Wang, Zhichao, Cheng, Huiyan, Xu, Huali, Yu, Xiaofeng, Sui, Dayun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - analogs & derivatives Adenosine - metabolism Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Atrophy Biomarkers, Tumor - antagonists & inhibitors Biomarkers, Tumor - genetics Computational Biology Datasets as Topic DNA methylation Female Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene set enrichment analysis Genes Humans Infant Kaplan-Meier Estimate Male Medical prognosis Methylation - drug effects Molecular Targeted Therapy - methods N6-methyladenosine Neuroblastoma Neuroblastoma - drug therapy Neuroblastoma - genetics Neuroblastoma - mortality Prediction models Prognosis Proportional Hazards Models Regression analysis Regression models Regulators Risk Assessment - methods Risk Factors RNA modification Survival Rate Therapeutic applications Transcriptome - drug effects Transcriptome - genetics Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!