Review of Potential Significance of Mutations of ADAMTS20, NF1 and PKHD1 Detected Using Next Generation Sequencing (NGS) in Dermal Fibrosarcoma Arising in Dermatofibrosarcoma Protuberans

We examined a status of fibrosarcoma arising in dermatofibrosarcoma protuberans of 64-year-old male patient. A dermal, solid, grayish-yellow, desmin-negative trichrome-bluish tumor measured 1.5 cm in diameter pT1a (edition 8 pTNM). It was composed of spindle cells. It was consistent with dermatofibr...

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Veröffentlicht in:	Folia Medica 2020-03, Vol.62 (1), p.17-22
Hauptverfasser:	Kowalik, Artur, Wincewicz, Andrzej, Zięba, Sebastian, Kopczynski, Janusz, Koda, Mariusz, Sulkowski, Stanisław, Kańczuga-Koda, Luiza, Góźdź, Stanisław
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAMTS20 Cancer Deoxyribonucleic acid dermatofibrosarcoma protuberans DNA fibrosa Fibrosarcoma Genes Genomics Mutation Phosphorylation Sarcoma Signal transduction Tumors
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