Synthesis and Antibacterial Activity Investigation of Novel Cuprous Oxide-Graphene Oxide Nanocomposites

Due to the increasing resistance of pathogens to antibiotics, novel antibacterial nanocomposite materials have been attracting increasing research interest. Herein, we report a facile synthetic method for a novel highly antibacterial nanocomposite based on graphene oxide (GO) nanosheets decorated wi...

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Veröffentlicht in:Chemistry letters 2020-06, Vol.49 (6), p.693-696
Hauptverfasser: Huang, Hua, Velmurugan, Murugan, Manibalan, Kesavan, Zhang, Qiang, Lu, Xinling, Wang, Yong, Lin, Jin-Ming
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container_end_page 696
container_issue 6
container_start_page 693
container_title Chemistry letters
container_volume 49
creator Huang, Hua
Velmurugan, Murugan
Manibalan, Kesavan
Zhang, Qiang
Lu, Xinling
Wang, Yong
Lin, Jin-Ming
description Due to the increasing resistance of pathogens to antibiotics, novel antibacterial nanocomposite materials have been attracting increasing research interest. Herein, we report a facile synthetic method for a novel highly antibacterial nanocomposite based on graphene oxide (GO) nanosheets decorated with cuprous oxide by a two-step method. The as-prepared nanocomposites were comprehensively characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), energy-dispersive X-ray (EDX) spectroscopy, field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). The nanocomposite was investigated for antibacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) using the medium dilution method and the disc diffusion method. The results showed that the synthesized Cu2O-GO has good antibacterial activities. At the nanocomposites concentration of 100 µg/mL, the inhibition rate against E. coli reached 68%, while the inhibition rate against. S. aureus reached 32%.
doi_str_mv 10.1246/cl.200128
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source Oxford University Press Journals All Titles (1996-Current)
subjects Antibacterial materials
Antibiotics
Copper oxides
Dilution
E coli
Electron microscopy
Field emission microscopy
Field emission spectroscopy
Graphene
Microscopy
Nanocomposites
Photoelectrons
Spectrum analysis
X ray photoelectron spectroscopy
title Synthesis and Antibacterial Activity Investigation of Novel Cuprous Oxide-Graphene Oxide Nanocomposites
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