1436-P: Association between Sleep Duration and Mortality among Adults with Type 2 Diabetes: A Prospective Cohort Study

Objective: We aimed to address the association of sleep duration and all-cause and cause-specific mortality (CVD, cancer and other causes) in people with type 2 diabetes. Research Design and Methods: The sample consisted of 24,212 adults with type 2 diabetes from the National Health Interview Survey (2004 to 2013). The relationship between sleep duration and mortality were investigated using Cox proportional hazards regression model. Results: A J-shaped relationship existed between sleep duration and all-cause mortality in people with type 2 diabetes. Compared to the reference group (7 hours/day), both shorter and longer sleep duration were significantly associated with increased risk of all-cause mortality. Similar associations were also observed for mortality from CVD, cancer, kidney disease, Alzheimer’s disease, and chronic lower respiratory diseases (CLRD). Greater risks of all-cause and CVD mortality were associated with longer sleep duration in men with a younger age of onset, as well as shorter sleep duration in those with both taking insulin and diabetes pills. Conclusions: In people with type 2 diabetes, sleeping less or more than 7 hours/day was associated with increased risk of all-cause and condition specific mortality. The association was more prominent in men with a younger age at diabetes onset and those taking diabetes pills and insulin.