1625-P: Association of Patient- and Disease-Related Factors with Glycemic Target Achievement in Type 1 Diabetes (T1D) in the SAGE Study
Most people with T1D do not achieve HbA1c targets, but this may vary with patient- and disease-related factors. SAGE was a multinational, cross-sectional study using data from medical records and interviews of eligible people with T1D for ≥1 year, aged ≥26 years (N=3858). The relationship between ea...
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| Veröffentlicht in: | Diabetes (New York, N.Y.) N.Y.), 2020-06, Vol.69 (Supplement_1) |
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| container_title | Diabetes (New York, N.Y.) |
| container_volume | 69 |
| creator | SEUFERT, JOCHEN IKEGAMI, HIROSHI BRETTE, SANDRINE PILORGET, VALERIE LAUAND, FELIPE WILMOT, EMMA G. RENARD, ERIC GAGLIARDINO, JUAN J. |
| description | Most people with T1D do not achieve HbA1c targets, but this may vary with patient- and disease-related factors.
SAGE was a multinational, cross-sectional study using data from medical records and interviews of eligible people with T1D for ≥1 year, aged ≥26 years (N=3858). The relationship between each group of selected factors (sociodemographics, diabetes complications and comorbidities, T1D treatment, structure and process of medical care) and HbA1c target achievement (both general [HbA1c |
| doi_str_mv | 10.2337/db20-1625-P |
| format | Article |
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SAGE was a multinational, cross-sectional study using data from medical records and interviews of eligible people with T1D for ≥1 year, aged ≥26 years (N=3858). The relationship between each group of selected factors (sociodemographics, diabetes complications and comorbidities, T1D treatment, structure and process of medical care) and HbA1c target achievement (both general [HbA1c <7 %] and individualized) were evaluated.
Overall, 24.3% of people achieved HbA1c <7 %; 20.9% achieved individualized targets. For both targets, better achievement was associated with: lower body mass index, diastolic blood pressure, and total daily insulin dose; ≥1 symptomatic hypoglycemic event (<54 mg/dL) within the last 3 months; higher levels of education; and having health insurance (Table). Poorer target achievement was associated with ≥1 severe hyperglycemic event leading to diabetic ketoacidosis within the last 6 months, microvascular complications, and dyslipidemia. Older people were more likely to achieve individualized targets while younger people were more likely to achieve HbA1c <7 %.
HbA1c target achievement remains a challenge but SAGE identified factors that appear to be associated with HbA1c target achievement, offering opportunities for intervention.</description><identifier>ISSN: 0012-1797</identifier><identifier>EISSN: 1939-327X</identifier><identifier>DOI: 10.2337/db20-1625-P</identifier><language>eng</language><publisher>New York: American Diabetes Association</publisher><subject>Blood pressure ; Body mass index ; Diabetes ; Diabetes mellitus (insulin dependent) ; Dyslipidemia ; Hyperglycemia ; Hypoglycemia ; Insulin ; Ketoacidosis ; Medical records ; Microvasculature ; Patients</subject><ispartof>Diabetes (New York, N.Y.), 2020-06, Vol.69 (Supplement_1)</ispartof><rights>Copyright American Diabetes Association Jun 1, 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids></links><search><creatorcontrib>SEUFERT, JOCHEN</creatorcontrib><creatorcontrib>IKEGAMI, HIROSHI</creatorcontrib><creatorcontrib>BRETTE, SANDRINE</creatorcontrib><creatorcontrib>PILORGET, VALERIE</creatorcontrib><creatorcontrib>LAUAND, FELIPE</creatorcontrib><creatorcontrib>WILMOT, EMMA G.</creatorcontrib><creatorcontrib>RENARD, ERIC</creatorcontrib><creatorcontrib>GAGLIARDINO, JUAN J.</creatorcontrib><title>1625-P: Association of Patient- and Disease-Related Factors with Glycemic Target Achievement in Type 1 Diabetes (T1D) in the SAGE Study</title><title>Diabetes (New York, N.Y.)</title><description>Most people with T1D do not achieve HbA1c targets, but this may vary with patient- and disease-related factors.
SAGE was a multinational, cross-sectional study using data from medical records and interviews of eligible people with T1D for ≥1 year, aged ≥26 years (N=3858). The relationship between each group of selected factors (sociodemographics, diabetes complications and comorbidities, T1D treatment, structure and process of medical care) and HbA1c target achievement (both general [HbA1c <7 %] and individualized) were evaluated.
Overall, 24.3% of people achieved HbA1c <7 %; 20.9% achieved individualized targets. For both targets, better achievement was associated with: lower body mass index, diastolic blood pressure, and total daily insulin dose; ≥1 symptomatic hypoglycemic event (<54 mg/dL) within the last 3 months; higher levels of education; and having health insurance (Table). Poorer target achievement was associated with ≥1 severe hyperglycemic event leading to diabetic ketoacidosis within the last 6 months, microvascular complications, and dyslipidemia. Older people were more likely to achieve individualized targets while younger people were more likely to achieve HbA1c <7 %.
HbA1c target achievement remains a challenge but SAGE identified factors that appear to be associated with HbA1c target achievement, offering opportunities for intervention.</description><subject>Blood pressure</subject><subject>Body mass index</subject><subject>Diabetes</subject><subject>Diabetes mellitus (insulin dependent)</subject><subject>Dyslipidemia</subject><subject>Hyperglycemia</subject><subject>Hypoglycemia</subject><subject>Insulin</subject><subject>Ketoacidosis</subject><subject>Medical records</subject><subject>Microvasculature</subject><subject>Patients</subject><issn>0012-1797</issn><issn>1939-327X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNotkNtKw0AQhhdRsFavfIEFbxRZ3UM2abwrPSkULDYX3i17mNiVNqnZrZIn8LVNqMzFDMw3_8_8CF0z-sCFyB6d4ZSwlEuyOkEDloucCJ69n6IBpYwTluXZOboI4ZNSmnY1QL9H-gmPQ6it19HXFa5LvOomqCLBunJ46gPoAOQNtjqCw3NtY90E_OPjBi-2rYWdt7jQzQdEPLYbD9-w666xr3DR7gGzTkIbiBDwbcGmd_0ibgCvx4sZXseDay_RWam3Aa7--xAV81kxeSbL18XLZLwkNk0kGaWcmYymOWQJMzJhzo5Am7T7xoKhDrhJIC8lKzM5spYBk8LJFFJHBRXGiiG6Ocrum_rrACGqz_rQVJ2j4gnLE8kllR11f6RsU4fQQKn2jd_pplWMqj5o1Qet-ujUSvwBHMVuZQ</recordid><startdate>20200601</startdate><enddate>20200601</enddate><creator>SEUFERT, JOCHEN</creator><creator>IKEGAMI, HIROSHI</creator><creator>BRETTE, SANDRINE</creator><creator>PILORGET, VALERIE</creator><creator>LAUAND, FELIPE</creator><creator>WILMOT, EMMA G.</creator><creator>RENARD, ERIC</creator><creator>GAGLIARDINO, JUAN J.</creator><general>American Diabetes Association</general><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>20200601</creationdate><title>1625-P: Association of Patient- and Disease-Related Factors with Glycemic Target Achievement in Type 1 Diabetes (T1D) in the SAGE Study</title><author>SEUFERT, JOCHEN ; IKEGAMI, HIROSHI ; BRETTE, SANDRINE ; PILORGET, VALERIE ; LAUAND, FELIPE ; WILMOT, EMMA G. ; RENARD, ERIC ; GAGLIARDINO, JUAN J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c645-8621b7069e741b541dc8eab6006ceb0de2b4e9f51f758cc1e153d56e6d0303bc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Blood pressure</topic><topic>Body mass index</topic><topic>Diabetes</topic><topic>Diabetes mellitus (insulin dependent)</topic><topic>Dyslipidemia</topic><topic>Hyperglycemia</topic><topic>Hypoglycemia</topic><topic>Insulin</topic><topic>Ketoacidosis</topic><topic>Medical records</topic><topic>Microvasculature</topic><topic>Patients</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SEUFERT, JOCHEN</creatorcontrib><creatorcontrib>IKEGAMI, HIROSHI</creatorcontrib><creatorcontrib>BRETTE, SANDRINE</creatorcontrib><creatorcontrib>PILORGET, VALERIE</creatorcontrib><creatorcontrib>LAUAND, FELIPE</creatorcontrib><creatorcontrib>WILMOT, EMMA G.</creatorcontrib><creatorcontrib>RENARD, ERIC</creatorcontrib><creatorcontrib>GAGLIARDINO, JUAN J.</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Diabetes (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SEUFERT, JOCHEN</au><au>IKEGAMI, HIROSHI</au><au>BRETTE, SANDRINE</au><au>PILORGET, VALERIE</au><au>LAUAND, FELIPE</au><au>WILMOT, EMMA G.</au><au>RENARD, ERIC</au><au>GAGLIARDINO, JUAN J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>1625-P: Association of Patient- and Disease-Related Factors with Glycemic Target Achievement in Type 1 Diabetes (T1D) in the SAGE Study</atitle><jtitle>Diabetes (New York, N.Y.)</jtitle><date>2020-06-01</date><risdate>2020</risdate><volume>69</volume><issue>Supplement_1</issue><issn>0012-1797</issn><eissn>1939-327X</eissn><abstract>Most people with T1D do not achieve HbA1c targets, but this may vary with patient- and disease-related factors.
SAGE was a multinational, cross-sectional study using data from medical records and interviews of eligible people with T1D for ≥1 year, aged ≥26 years (N=3858). The relationship between each group of selected factors (sociodemographics, diabetes complications and comorbidities, T1D treatment, structure and process of medical care) and HbA1c target achievement (both general [HbA1c <7 %] and individualized) were evaluated.
Overall, 24.3% of people achieved HbA1c <7 %; 20.9% achieved individualized targets. For both targets, better achievement was associated with: lower body mass index, diastolic blood pressure, and total daily insulin dose; ≥1 symptomatic hypoglycemic event (<54 mg/dL) within the last 3 months; higher levels of education; and having health insurance (Table). Poorer target achievement was associated with ≥1 severe hyperglycemic event leading to diabetic ketoacidosis within the last 6 months, microvascular complications, and dyslipidemia. Older people were more likely to achieve individualized targets while younger people were more likely to achieve HbA1c <7 %.
HbA1c target achievement remains a challenge but SAGE identified factors that appear to be associated with HbA1c target achievement, offering opportunities for intervention.</abstract><cop>New York</cop><pub>American Diabetes Association</pub><doi>10.2337/db20-1625-P</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0012-1797 |
| ispartof | Diabetes (New York, N.Y.), 2020-06, Vol.69 (Supplement_1) |
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| language | eng |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Blood pressure Body mass index Diabetes Diabetes mellitus (insulin dependent) Dyslipidemia Hyperglycemia Hypoglycemia Insulin Ketoacidosis Medical records Microvasculature Patients |
| title | 1625-P: Association of Patient- and Disease-Related Factors with Glycemic Target Achievement in Type 1 Diabetes (T1D) in the SAGE Study |
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