85-LB: Freestyle Libre System Use Associated with Reduction in Acute Diabetes Events and All-Cause Hospitalizations in Patients with Type 2 Diabetes without Bolus Insulin

Data on the benefit of continuous glucose monitors (CGM) in people with diabetes not using intensive insulin therapy is limited. We describe clinical outcomes after a FreeStyle Libre® system purchase in people with type 2 diabetes (T2D) not using bolus insulin. IBM MarketScan™ Commercial Claims and...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2020-06, Vol.69 (Supplement_1)
Hauptverfasser:	MILLER, EDEN, KERR, MATTHEW S.D., ROBERTS, GREGORY J., SOUTO, DIANA, NABUTOVSKY, YELENA, WRIGHT, EUGENE
Format:	Artikel
Sprache:	eng
Schlagworte:	Diabetes Diabetes mellitus (non-insulin dependent) Diagnosis Hospitalization Hypoglycemia Insulin
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container_title	Diabetes (New York, N.Y.)
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creator	MILLER, EDEN KERR, MATTHEW S.D. ROBERTS, GREGORY J. SOUTO, DIANA NABUTOVSKY, YELENA WRIGHT, EUGENE
description	Data on the benefit of continuous glucose monitors (CGM) in people with diabetes not using intensive insulin therapy is limited. We describe clinical outcomes after a FreeStyle Libre® system purchase in people with type 2 diabetes (T2D) not using bolus insulin. IBM MarketScan™ Commercial Claims and Medicare Supplemental databases were used in this retrospective, observational analysis. MarketScan contains insurance billing claims for inpatient, outpatient, and pharmacy. Cohort requirements included: de novo CGM, FreeStyle Libre system purchase 2017 Q4-2018 Q4, T2D diagnosis, ≥18 years old, no fast-/short-acting insulin, ≥6-months pre-index observation time. Primary outcome was acute diabetes events (ADE): hospitalization with hyper-/hypoglycemia as primary diagnosis or outpatient emergency with same codes. Secondary outcome was all-cause hospitalization. Andersen-Gill Cox regression compared event rates 6-months pre-/post-index. The cohort (n= 7,167, age 53.3±9.5 years, 51.5% male, avg. post-index follow-up 155 days) saw a reduction in ADE from 0.071 to 0.052 events/pt-yr (HR: 0.70 [0.57 0.85]; P:
doi_str_mv	10.2337/db20-85-LB
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We describe clinical outcomes after a FreeStyle Libre® system purchase in people with type 2 diabetes (T2D) not using bolus insulin. IBM MarketScan™ Commercial Claims and Medicare Supplemental databases were used in this retrospective, observational analysis. MarketScan contains insurance billing claims for inpatient, outpatient, and pharmacy. Cohort requirements included: de novo CGM, FreeStyle Libre system purchase 2017 Q4-2018 Q4, T2D diagnosis, ≥18 years old, no fast-/short-acting insulin, ≥6-months pre-index observation time. Primary outcome was acute diabetes events (ADE): hospitalization with hyper-/hypoglycemia as primary diagnosis or outpatient emergency with same codes. Secondary outcome was all-cause hospitalization. Andersen-Gill Cox regression compared event rates 6-months pre-/post-index. The cohort (n= 7,167, age 53.3±9.5 years, 51.5% male, avg. post-index follow-up 155 days) saw a reduction in ADE from 0.071 to 0.052 events/pt-yr (HR: 0.70 [0.57 0.85]; P:<0.001). Hospitalizations reduced from 0.180 to 0.161 events/pt-yr (HR: 0.87 [0.78 0.98]; P: 0.025). 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We describe clinical outcomes after a FreeStyle Libre® system purchase in people with type 2 diabetes (T2D) not using bolus insulin. IBM MarketScan™ Commercial Claims and Medicare Supplemental databases were used in this retrospective, observational analysis. MarketScan contains insurance billing claims for inpatient, outpatient, and pharmacy. Cohort requirements included: de novo CGM, FreeStyle Libre system purchase 2017 Q4-2018 Q4, T2D diagnosis, ≥18 years old, no fast-/short-acting insulin, ≥6-months pre-index observation time. Primary outcome was acute diabetes events (ADE): hospitalization with hyper-/hypoglycemia as primary diagnosis or outpatient emergency with same codes. Secondary outcome was all-cause hospitalization. Andersen-Gill Cox regression compared event rates 6-months pre-/post-index. The cohort (n= 7,167, age 53.3±9.5 years, 51.5% male, avg. post-index follow-up 155 days) saw a reduction in ADE from 0.071 to 0.052 events/pt-yr (HR: 0.70 [0.57 0.85]; P:<0.001). Hospitalizations reduced from 0.180 to 0.161 events/pt-yr (HR: 0.87 [0.78 0.98]; P: 0.025). After FreeStyle Libre system purchase, T2D patients not on bolus insulin had lower rates of ADE and all-cause hospitalization.</abstract><cop>New York</cop><pub>American Diabetes Association</pub><doi>10.2337/db20-85-LB</doi></addata></record>
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source	Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects	Diabetes Diabetes mellitus (non-insulin dependent) Diagnosis Hospitalization Hypoglycemia Insulin
title	85-LB: Freestyle Libre System Use Associated with Reduction in Acute Diabetes Events and All-Cause Hospitalizations in Patients with Type 2 Diabetes without Bolus Insulin
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