Dehydroxyalkylative halogenation of C(aryl)-C bonds of aryl alcohols
We herein report Cu mediated side-directed dehydroxyalkylative halogenation of aryl alcohols. C(aryl)-C bonds of aryl alcohols were effectively cleaved, affording the corresponding aryl chlorides, bromides and iodides in excellent yields. Aryl alcohols could serve as both aromatic electrophilic and...
Gespeichert in:
| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2020-07, Vol.56 (52), p.712-7123 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 7123 |
|---|---|
| container_issue | 52 |
| container_start_page | 712 |
| container_title | Chemical communications (Cambridge, England) |
| container_volume | 56 |
| creator | Liu, Mingyang Zhang, Zhanrong Liu, Huizhen Wu, Tianbin Han, Buxing |
| description | We herein report Cu mediated side-directed dehydroxyalkylative halogenation of aryl alcohols. C(aryl)-C bonds of aryl alcohols were effectively cleaved, affording the corresponding aryl chlorides, bromides and iodides in excellent yields. Aryl alcohols could serve as both aromatic electrophilic and radical synthetic equivalents during the reaction.
Aryl alcohols which acted as aromatic electrophilic and radical synthetic equivalents were effectively converted to aryl halides
via
Cu mediated side-directed dehydroxyalkylative halogenation of C(aryl)-C bonds. |
| doi_str_mv | 10.1039/d0cc02306j |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_journals_2418731051</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2418731051</sourcerecordid><originalsourceid>FETCH-LOGICAL-c363t-a24cf6926f3297a4b20d30bb63df6e33989e6b58dbf8e909e1a4fa5e3f3b56ac3</originalsourceid><addsrcrecordid>eNp90c9PwyAUB3BiNG5OL941NV6mSRX6gJWj6fyZJV408dZQCm6TlVlWY_97mZsz8SAX4PHJC3xB6JDgC4JBXJZYKZwA5tMt1CXAacxo-rK9XDMRD4CyDtrzforDICzdRR1IKEtTCl00HOpxW9bus5X2rbVyMfnQ0Vha96qrsHFV5EyU9WXd2rM4iwpXlX5ZWhYiaZUbO-v30Y6R1uuD9dxDzzfXT9ldPHq8vc-uRrECDotYJlQZLhJuIBEDSYsEl4CLgkNpuAYQqdC8YGlZmFQLLDSR1EimwUDBuFTQQ_1V33nt3hvtF_ls4pW2VlbaNT5PKB4AYcBooKd_6NQ1dRVuFxRJA8OMBHW-Uqp23tfa5PN6MgtvywnOl9nmQ5xl39k-BHy8btkUM11u6E-YAZysQO3V5vT3c_J5aYI5-s_AFzuBiDk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2418731051</pqid></control><display><type>article</type><title>Dehydroxyalkylative halogenation of C(aryl)-C bonds of aryl alcohols</title><source>Royal Society Of Chemistry Journals 2008-</source><source>Alma/SFX Local Collection</source><creator>Liu, Mingyang ; Zhang, Zhanrong ; Liu, Huizhen ; Wu, Tianbin ; Han, Buxing</creator><creatorcontrib>Liu, Mingyang ; Zhang, Zhanrong ; Liu, Huizhen ; Wu, Tianbin ; Han, Buxing</creatorcontrib><description>We herein report Cu mediated side-directed dehydroxyalkylative halogenation of aryl alcohols. C(aryl)-C bonds of aryl alcohols were effectively cleaved, affording the corresponding aryl chlorides, bromides and iodides in excellent yields. Aryl alcohols could serve as both aromatic electrophilic and radical synthetic equivalents during the reaction.
Aryl alcohols which acted as aromatic electrophilic and radical synthetic equivalents were effectively converted to aryl halides
via
Cu mediated side-directed dehydroxyalkylative halogenation of C(aryl)-C bonds.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/d0cc02306j</identifier><identifier>PMID: 32458843</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Alcohol ; Alcohols ; Aromatic compounds ; Bromides ; Halogenation ; Iodides</subject><ispartof>Chemical communications (Cambridge, England), 2020-07, Vol.56 (52), p.712-7123</ispartof><rights>Copyright Royal Society of Chemistry 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c363t-a24cf6926f3297a4b20d30bb63df6e33989e6b58dbf8e909e1a4fa5e3f3b56ac3</citedby><cites>FETCH-LOGICAL-c363t-a24cf6926f3297a4b20d30bb63df6e33989e6b58dbf8e909e1a4fa5e3f3b56ac3</cites><orcidid>0000-0002-6801-7816 ; 0000-0003-0440-809X ; 0000-0002-1334-9637 ; 0000-0002-2187-9654 ; 0000-0002-6643-5096</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32458843$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Mingyang</creatorcontrib><creatorcontrib>Zhang, Zhanrong</creatorcontrib><creatorcontrib>Liu, Huizhen</creatorcontrib><creatorcontrib>Wu, Tianbin</creatorcontrib><creatorcontrib>Han, Buxing</creatorcontrib><title>Dehydroxyalkylative halogenation of C(aryl)-C bonds of aryl alcohols</title><title>Chemical communications (Cambridge, England)</title><addtitle>Chem Commun (Camb)</addtitle><description>We herein report Cu mediated side-directed dehydroxyalkylative halogenation of aryl alcohols. C(aryl)-C bonds of aryl alcohols were effectively cleaved, affording the corresponding aryl chlorides, bromides and iodides in excellent yields. Aryl alcohols could serve as both aromatic electrophilic and radical synthetic equivalents during the reaction.
Aryl alcohols which acted as aromatic electrophilic and radical synthetic equivalents were effectively converted to aryl halides
via
Cu mediated side-directed dehydroxyalkylative halogenation of C(aryl)-C bonds.</description><subject>Alcohol</subject><subject>Alcohols</subject><subject>Aromatic compounds</subject><subject>Bromides</subject><subject>Halogenation</subject><subject>Iodides</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp90c9PwyAUB3BiNG5OL941NV6mSRX6gJWj6fyZJV408dZQCm6TlVlWY_97mZsz8SAX4PHJC3xB6JDgC4JBXJZYKZwA5tMt1CXAacxo-rK9XDMRD4CyDtrzforDICzdRR1IKEtTCl00HOpxW9bus5X2rbVyMfnQ0Vha96qrsHFV5EyU9WXd2rM4iwpXlX5ZWhYiaZUbO-v30Y6R1uuD9dxDzzfXT9ldPHq8vc-uRrECDotYJlQZLhJuIBEDSYsEl4CLgkNpuAYQqdC8YGlZmFQLLDSR1EimwUDBuFTQQ_1V33nt3hvtF_ls4pW2VlbaNT5PKB4AYcBooKd_6NQ1dRVuFxRJA8OMBHW-Uqp23tfa5PN6MgtvywnOl9nmQ5xl39k-BHy8btkUM11u6E-YAZysQO3V5vT3c_J5aYI5-s_AFzuBiDk</recordid><startdate>20200704</startdate><enddate>20200704</enddate><creator>Liu, Mingyang</creator><creator>Zhang, Zhanrong</creator><creator>Liu, Huizhen</creator><creator>Wu, Tianbin</creator><creator>Han, Buxing</creator><general>Royal Society of Chemistry</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-6801-7816</orcidid><orcidid>https://orcid.org/0000-0003-0440-809X</orcidid><orcidid>https://orcid.org/0000-0002-1334-9637</orcidid><orcidid>https://orcid.org/0000-0002-2187-9654</orcidid><orcidid>https://orcid.org/0000-0002-6643-5096</orcidid></search><sort><creationdate>20200704</creationdate><title>Dehydroxyalkylative halogenation of C(aryl)-C bonds of aryl alcohols</title><author>Liu, Mingyang ; Zhang, Zhanrong ; Liu, Huizhen ; Wu, Tianbin ; Han, Buxing</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c363t-a24cf6926f3297a4b20d30bb63df6e33989e6b58dbf8e909e1a4fa5e3f3b56ac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Alcohol</topic><topic>Alcohols</topic><topic>Aromatic compounds</topic><topic>Bromides</topic><topic>Halogenation</topic><topic>Iodides</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, Mingyang</creatorcontrib><creatorcontrib>Zhang, Zhanrong</creatorcontrib><creatorcontrib>Liu, Huizhen</creatorcontrib><creatorcontrib>Wu, Tianbin</creatorcontrib><creatorcontrib>Han, Buxing</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Mingyang</au><au>Zhang, Zhanrong</au><au>Liu, Huizhen</au><au>Wu, Tianbin</au><au>Han, Buxing</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dehydroxyalkylative halogenation of C(aryl)-C bonds of aryl alcohols</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><addtitle>Chem Commun (Camb)</addtitle><date>2020-07-04</date><risdate>2020</risdate><volume>56</volume><issue>52</issue><spage>712</spage><epage>7123</epage><pages>712-7123</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>We herein report Cu mediated side-directed dehydroxyalkylative halogenation of aryl alcohols. C(aryl)-C bonds of aryl alcohols were effectively cleaved, affording the corresponding aryl chlorides, bromides and iodides in excellent yields. Aryl alcohols could serve as both aromatic electrophilic and radical synthetic equivalents during the reaction.
Aryl alcohols which acted as aromatic electrophilic and radical synthetic equivalents were effectively converted to aryl halides
via
Cu mediated side-directed dehydroxyalkylative halogenation of C(aryl)-C bonds.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>32458843</pmid><doi>10.1039/d0cc02306j</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0002-6801-7816</orcidid><orcidid>https://orcid.org/0000-0003-0440-809X</orcidid><orcidid>https://orcid.org/0000-0002-1334-9637</orcidid><orcidid>https://orcid.org/0000-0002-2187-9654</orcidid><orcidid>https://orcid.org/0000-0002-6643-5096</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2020-07, Vol.56 (52), p.712-7123 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_proquest_journals_2418731051 |
| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Alcohol Alcohols Aromatic compounds Bromides Halogenation Iodides |
| title | Dehydroxyalkylative halogenation of C(aryl)-C bonds of aryl alcohols |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T19%3A32%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Dehydroxyalkylative%20halogenation%20of%20C(aryl)-C%20bonds%20of%20aryl%20alcohols&rft.jtitle=Chemical%20communications%20(Cambridge,%20England)&rft.au=Liu,%20Mingyang&rft.date=2020-07-04&rft.volume=56&rft.issue=52&rft.spage=712&rft.epage=7123&rft.pages=712-7123&rft.issn=1359-7345&rft.eissn=1364-548X&rft_id=info:doi/10.1039/d0cc02306j&rft_dat=%3Cproquest_pubme%3E2418731051%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2418731051&rft_id=info:pmid/32458843&rfr_iscdi=true |