Xanthogranuloma of the sellar region
The incidence of diagnosed xanthogranuloma of the sellar region is very low [1, 2, 5, 6]. We report about two cases 1) in a 57-year-old female and 2) in a 5-year-old boy. In both cases radiographic findings revealed an inhomogeneous, contrast enhancing sellar lesion. Histopathology showed the typica...
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description | The incidence of diagnosed xanthogranuloma of the sellar region is very low [1, 2, 5, 6]. We report about two cases 1) in a 57-year-old female and 2) in a 5-year-old boy. In both cases radiographic findings revealed an inhomogeneous, contrast enhancing sellar lesion. Histopathology showed the typical features of a xanthogranuloma of the sellar region with cholesterol clefts, lympho-plasmacellular infiltrates, marked hemosiderin deposits, multinucleated foreign body giant cells around cholesterol clefts, accumulation of macrophages and only small epithelial cell clusters [6]. As xanthogranuloma of the sellar region are rarely diagnosed we want to draw attention to this rather unusual diagnosis. |
doi_str_mv | 10.1007/s00701-005-0700-6 |
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We report about two cases 1) in a 57-year-old female and 2) in a 5-year-old boy. In both cases radiographic findings revealed an inhomogeneous, contrast enhancing sellar lesion. Histopathology showed the typical features of a xanthogranuloma of the sellar region with cholesterol clefts, lympho-plasmacellular infiltrates, marked hemosiderin deposits, multinucleated foreign body giant cells around cholesterol clefts, accumulation of macrophages and only small epithelial cell clusters [6]. As xanthogranuloma of the sellar region are rarely diagnosed we want to draw attention to this rather unusual diagnosis.</description><identifier>ISSN: 0001-6268</identifier><identifier>EISSN: 0942-0940</identifier><identifier>DOI: 10.1007/s00701-005-0700-6</identifier><identifier>PMID: 16341628</identifier><language>eng</language><publisher>Austria: Springer Nature B.V</publisher><subject>Child, Preschool ; Cholesterol ; Cholesterol - metabolism ; Craniopharyngioma - diagnosis ; Diagnosis, Differential ; Epithelial cells ; Female ; Giant cells ; Giant Cells, Foreign-Body - pathology ; Hemosiderin - metabolism ; Humans ; Hypopituitarism - etiology ; Hypopituitarism - physiopathology ; Hypopituitarism - surgery ; Lymphocytes - pathology ; Macrophages ; Macrophages - pathology ; Male ; Middle Aged ; Neurosurgical Procedures ; Pituitary Gland - pathology ; Pituitary Gland - physiopathology ; Pituitary Gland - surgery ; Postoperative Complications - etiology ; Postoperative Complications - physiopathology ; Postoperative Complications - therapy ; Sella Turcica - pathology ; Sella Turcica - physiopathology ; Sella Turcica - surgery ; Skull Base Neoplasms - diagnosis ; Skull Base Neoplasms - physiopathology ; Skull Base Neoplasms - surgery ; Treatment Outcome ; Xanthogranuloma, Juvenile - diagnosis ; Xanthogranuloma, Juvenile - physiopathology ; Xanthogranuloma, Juvenile - surgery</subject><ispartof>Acta neurochirurgica, 2006-04, Vol.148 (4), p.473-477</ispartof><rights>Springer-Verlag/Wien 2005.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c296t-8dd61140c0176aa815da8f3b163e00371c1339bebef9bdb2886ec44087d5421f3</citedby><cites>FETCH-LOGICAL-c296t-8dd61140c0176aa815da8f3b163e00371c1339bebef9bdb2886ec44087d5421f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16341628$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jung, C S</creatorcontrib><creatorcontrib>Schänzer, A</creatorcontrib><creatorcontrib>Hattingen, E</creatorcontrib><creatorcontrib>Plate, K H</creatorcontrib><creatorcontrib>Seifert, V</creatorcontrib><title>Xanthogranuloma of the sellar region</title><title>Acta neurochirurgica</title><addtitle>Acta Neurochir (Wien)</addtitle><description>The incidence of diagnosed xanthogranuloma of the sellar region is very low [1, 2, 5, 6]. We report about two cases 1) in a 57-year-old female and 2) in a 5-year-old boy. In both cases radiographic findings revealed an inhomogeneous, contrast enhancing sellar lesion. Histopathology showed the typical features of a xanthogranuloma of the sellar region with cholesterol clefts, lympho-plasmacellular infiltrates, marked hemosiderin deposits, multinucleated foreign body giant cells around cholesterol clefts, accumulation of macrophages and only small epithelial cell clusters [6]. As xanthogranuloma of the sellar region are rarely diagnosed we want to draw attention to this rather unusual diagnosis.</description><subject>Child, Preschool</subject><subject>Cholesterol</subject><subject>Cholesterol - metabolism</subject><subject>Craniopharyngioma - diagnosis</subject><subject>Diagnosis, Differential</subject><subject>Epithelial cells</subject><subject>Female</subject><subject>Giant cells</subject><subject>Giant Cells, Foreign-Body - pathology</subject><subject>Hemosiderin - metabolism</subject><subject>Humans</subject><subject>Hypopituitarism - etiology</subject><subject>Hypopituitarism - physiopathology</subject><subject>Hypopituitarism - surgery</subject><subject>Lymphocytes - pathology</subject><subject>Macrophages</subject><subject>Macrophages - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neurosurgical Procedures</subject><subject>Pituitary Gland - pathology</subject><subject>Pituitary Gland - physiopathology</subject><subject>Pituitary Gland - surgery</subject><subject>Postoperative Complications - etiology</subject><subject>Postoperative Complications - physiopathology</subject><subject>Postoperative Complications - therapy</subject><subject>Sella Turcica - pathology</subject><subject>Sella Turcica - physiopathology</subject><subject>Sella Turcica - surgery</subject><subject>Skull Base Neoplasms - diagnosis</subject><subject>Skull Base Neoplasms - physiopathology</subject><subject>Skull Base Neoplasms - surgery</subject><subject>Treatment Outcome</subject><subject>Xanthogranuloma, Juvenile - diagnosis</subject><subject>Xanthogranuloma, Juvenile - physiopathology</subject><subject>Xanthogranuloma, Juvenile - surgery</subject><issn>0001-6268</issn><issn>0942-0940</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpFkE1LxDAQhoMo7rr6A7xIQa_RmSRN06Ms6wcseFHwFtI23Q_aZk3ag__elBa8zAfzzjvDQ8gtwiMCZE8hBkAKkNJYAJVnZAm5YDQGOI81xKlkUi3IVQjH2LFM8EuyQMkFSqaW5OHbdP3e7bzphsa1JnF10u9tEmzTGJ94uzu47ppc1KYJ9mbOK_L1svlcv9Htx-v7-nlLS5bLnqqqkogCSsBMGqMwrYyqeRGvWQCeYYmc54UtbJ0XVcGUkrYUAlRWpYJhzVfkfvI9efcz2NDroxt8F09qNv6bq0xBVOGkKr0Lwdtan_yhNf5XI-iRi5646MhFj1y0jDt3s_NQtLb635hB8D_rq1tn</recordid><startdate>200604</startdate><enddate>200604</enddate><creator>Jung, C S</creator><creator>Schänzer, A</creator><creator>Hattingen, E</creator><creator>Plate, K H</creator><creator>Seifert, V</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>200604</creationdate><title>Xanthogranuloma of the sellar region</title><author>Jung, C S ; Schänzer, A ; Hattingen, E ; Plate, K H ; Seifert, V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c296t-8dd61140c0176aa815da8f3b163e00371c1339bebef9bdb2886ec44087d5421f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Child, Preschool</topic><topic>Cholesterol</topic><topic>Cholesterol - metabolism</topic><topic>Craniopharyngioma - diagnosis</topic><topic>Diagnosis, Differential</topic><topic>Epithelial cells</topic><topic>Female</topic><topic>Giant cells</topic><topic>Giant Cells, Foreign-Body - pathology</topic><topic>Hemosiderin - metabolism</topic><topic>Humans</topic><topic>Hypopituitarism - etiology</topic><topic>Hypopituitarism - physiopathology</topic><topic>Hypopituitarism - surgery</topic><topic>Lymphocytes - pathology</topic><topic>Macrophages</topic><topic>Macrophages - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neurosurgical Procedures</topic><topic>Pituitary Gland - pathology</topic><topic>Pituitary Gland - physiopathology</topic><topic>Pituitary Gland - surgery</topic><topic>Postoperative Complications - etiology</topic><topic>Postoperative Complications - physiopathology</topic><topic>Postoperative Complications - therapy</topic><topic>Sella Turcica - pathology</topic><topic>Sella Turcica - physiopathology</topic><topic>Sella Turcica - surgery</topic><topic>Skull Base Neoplasms - diagnosis</topic><topic>Skull Base Neoplasms - physiopathology</topic><topic>Skull Base Neoplasms - surgery</topic><topic>Treatment Outcome</topic><topic>Xanthogranuloma, Juvenile - diagnosis</topic><topic>Xanthogranuloma, Juvenile - physiopathology</topic><topic>Xanthogranuloma, Juvenile - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jung, C S</creatorcontrib><creatorcontrib>Schänzer, A</creatorcontrib><creatorcontrib>Hattingen, E</creatorcontrib><creatorcontrib>Plate, K H</creatorcontrib><creatorcontrib>Seifert, V</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Acta neurochirurgica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jung, C S</au><au>Schänzer, A</au><au>Hattingen, E</au><au>Plate, K H</au><au>Seifert, V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Xanthogranuloma of the sellar region</atitle><jtitle>Acta neurochirurgica</jtitle><addtitle>Acta Neurochir (Wien)</addtitle><date>2006-04</date><risdate>2006</risdate><volume>148</volume><issue>4</issue><spage>473</spage><epage>477</epage><pages>473-477</pages><issn>0001-6268</issn><eissn>0942-0940</eissn><abstract>The incidence of diagnosed xanthogranuloma of the sellar region is very low [1, 2, 5, 6]. 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subjects | Child, Preschool Cholesterol Cholesterol - metabolism Craniopharyngioma - diagnosis Diagnosis, Differential Epithelial cells Female Giant cells Giant Cells, Foreign-Body - pathology Hemosiderin - metabolism Humans Hypopituitarism - etiology Hypopituitarism - physiopathology Hypopituitarism - surgery Lymphocytes - pathology Macrophages Macrophages - pathology Male Middle Aged Neurosurgical Procedures Pituitary Gland - pathology Pituitary Gland - physiopathology Pituitary Gland - surgery Postoperative Complications - etiology Postoperative Complications - physiopathology Postoperative Complications - therapy Sella Turcica - pathology Sella Turcica - physiopathology Sella Turcica - surgery Skull Base Neoplasms - diagnosis Skull Base Neoplasms - physiopathology Skull Base Neoplasms - surgery Treatment Outcome Xanthogranuloma, Juvenile - diagnosis Xanthogranuloma, Juvenile - physiopathology Xanthogranuloma, Juvenile - surgery |
title | Xanthogranuloma of the sellar region |
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