Xanthogranuloma of the sellar region

The incidence of diagnosed xanthogranuloma of the sellar region is very low [1, 2, 5, 6]. We report about two cases 1) in a 57-year-old female and 2) in a 5-year-old boy. In both cases radiographic findings revealed an inhomogeneous, contrast enhancing sellar lesion. Histopathology showed the typica...

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Veröffentlicht in:Acta neurochirurgica 2006-04, Vol.148 (4), p.473-477
Hauptverfasser: Jung, C S, Schänzer, A, Hattingen, E, Plate, K H, Seifert, V
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container_title Acta neurochirurgica
container_volume 148
creator Jung, C S
Schänzer, A
Hattingen, E
Plate, K H
Seifert, V
description The incidence of diagnosed xanthogranuloma of the sellar region is very low [1, 2, 5, 6]. We report about two cases 1) in a 57-year-old female and 2) in a 5-year-old boy. In both cases radiographic findings revealed an inhomogeneous, contrast enhancing sellar lesion. Histopathology showed the typical features of a xanthogranuloma of the sellar region with cholesterol clefts, lympho-plasmacellular infiltrates, marked hemosiderin deposits, multinucleated foreign body giant cells around cholesterol clefts, accumulation of macrophages and only small epithelial cell clusters [6]. As xanthogranuloma of the sellar region are rarely diagnosed we want to draw attention to this rather unusual diagnosis.
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subjects Child, Preschool
Cholesterol
Cholesterol - metabolism
Craniopharyngioma - diagnosis
Diagnosis, Differential
Epithelial cells
Female
Giant cells
Giant Cells, Foreign-Body - pathology
Hemosiderin - metabolism
Humans
Hypopituitarism - etiology
Hypopituitarism - physiopathology
Hypopituitarism - surgery
Lymphocytes - pathology
Macrophages
Macrophages - pathology
Male
Middle Aged
Neurosurgical Procedures
Pituitary Gland - pathology
Pituitary Gland - physiopathology
Pituitary Gland - surgery
Postoperative Complications - etiology
Postoperative Complications - physiopathology
Postoperative Complications - therapy
Sella Turcica - pathology
Sella Turcica - physiopathology
Sella Turcica - surgery
Skull Base Neoplasms - diagnosis
Skull Base Neoplasms - physiopathology
Skull Base Neoplasms - surgery
Treatment Outcome
Xanthogranuloma, Juvenile - diagnosis
Xanthogranuloma, Juvenile - physiopathology
Xanthogranuloma, Juvenile - surgery
title Xanthogranuloma of the sellar region
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