Coronary surgery in dialysis-dependent patients with end stage renal failure
The number of patients with dialysis-dependent end stage renal failure (ESRF) and coronary heart disease (CAD) has increased in recent years. Coronary artery bypass grafting (CABG) has become the standard treatment for CAD in this patient group, but is still considered as a risk procedure due to inc...
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Veröffentlicht in: | Clinical research in cardiology 2005-10, Vol.94 (10), p.679-683 |
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creator | Tugtekin, S M Alexiou, K Georgi, Ch Kappert, U Knaut, M Matschke, K |
description | The number of patients with dialysis-dependent end stage renal failure (ESRF) and coronary heart disease (CAD) has increased in recent years. Coronary artery bypass grafting (CABG) has become the standard treatment for CAD in this patient group, but is still considered as a risk procedure due to increased mortality and morbidity. In a retrospective study we analyzed our clinical results of isolated CABG in 40 dialysis-dependent patients with ESRF (5 female and 35 male, mean age 65+/-8.4 years) and the use of extracorporeal circulation. The perioperative control group comprised 51 patients (10 female and 41 male, mean age 67+/-7.3 years) with normal renal function and isolated CABG. Demographic and preoperative data were comparable in both groups. Hospital mortality was 2.5% in patients with ESRF and 0% in patients with normal renal function. Morbidity was comparable in both groups. The mean number of grafts was 3.1+/-0.9 in the dialysis group and 2.9+/-0.8 in the control group. In the follow-up of the dialysis group (34+/-23 months) 8 patients died. CABG in patients with dialysis-dependent ESRF can be performed with good clinical results and morbidity comparable to patients with normal renal function. |
doi_str_mv | 10.1007/s00392-005-0286-2 |
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Coronary artery bypass grafting (CABG) has become the standard treatment for CAD in this patient group, but is still considered as a risk procedure due to increased mortality and morbidity. In a retrospective study we analyzed our clinical results of isolated CABG in 40 dialysis-dependent patients with ESRF (5 female and 35 male, mean age 65+/-8.4 years) and the use of extracorporeal circulation. The perioperative control group comprised 51 patients (10 female and 41 male, mean age 67+/-7.3 years) with normal renal function and isolated CABG. Demographic and preoperative data were comparable in both groups. Hospital mortality was 2.5% in patients with ESRF and 0% in patients with normal renal function. Morbidity was comparable in both groups. The mean number of grafts was 3.1+/-0.9 in the dialysis group and 2.9+/-0.8 in the control group. In the follow-up of the dialysis group (34+/-23 months) 8 patients died. CABG in patients with dialysis-dependent ESRF can be performed with good clinical results and morbidity comparable to patients with normal renal function.</description><identifier>ISSN: 0300-5860</identifier><identifier>ISSN: 1861-0684</identifier><identifier>EISSN: 1435-1285</identifier><identifier>EISSN: 1861-0692</identifier><identifier>DOI: 10.1007/s00392-005-0286-2</identifier><identifier>PMID: 16200483</identifier><language>eng</language><publisher>Germany: Springer Nature B.V</publisher><subject>Aged ; Bypass ; Cardiovascular disease ; Cardiovascular diseases ; Coronary artery ; Coronary Artery Bypass - mortality ; Coronary artery disease ; Dialysis ; Extracorporeal Circulation - mortality ; Female ; Germany - epidemiology ; Heart diseases ; Heart surgery ; Hemodialysis ; Humans ; Kidney Failure, Chronic - mortality ; Kidney Failure, Chronic - rehabilitation ; Male ; Morbidity ; Mortality ; Patients ; Prevalence ; Renal Dialysis - mortality ; Renal failure ; Renal function ; Retrospective Studies ; Risk Assessment - methods ; Risk Factors ; Treatment Outcome</subject><ispartof>Clinical research in cardiology, 2005-10, Vol.94 (10), p.679-683</ispartof><rights>Steinkopff-Verlag 2005.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c279t-1d45f38836a51920dc2c31ecf8583f57a86c9111ed1b6a894bbccd2fa03a509c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16200483$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tugtekin, S M</creatorcontrib><creatorcontrib>Alexiou, K</creatorcontrib><creatorcontrib>Georgi, Ch</creatorcontrib><creatorcontrib>Kappert, U</creatorcontrib><creatorcontrib>Knaut, M</creatorcontrib><creatorcontrib>Matschke, K</creatorcontrib><title>Coronary surgery in dialysis-dependent patients with end stage renal failure</title><title>Clinical research in cardiology</title><addtitle>Z Kardiol</addtitle><description>The number of patients with dialysis-dependent end stage renal failure (ESRF) and coronary heart disease (CAD) has increased in recent years. Coronary artery bypass grafting (CABG) has become the standard treatment for CAD in this patient group, but is still considered as a risk procedure due to increased mortality and morbidity. In a retrospective study we analyzed our clinical results of isolated CABG in 40 dialysis-dependent patients with ESRF (5 female and 35 male, mean age 65+/-8.4 years) and the use of extracorporeal circulation. The perioperative control group comprised 51 patients (10 female and 41 male, mean age 67+/-7.3 years) with normal renal function and isolated CABG. Demographic and preoperative data were comparable in both groups. Hospital mortality was 2.5% in patients with ESRF and 0% in patients with normal renal function. Morbidity was comparable in both groups. The mean number of grafts was 3.1+/-0.9 in the dialysis group and 2.9+/-0.8 in the control group. In the follow-up of the dialysis group (34+/-23 months) 8 patients died. CABG in patients with dialysis-dependent ESRF can be performed with good clinical results and morbidity comparable to patients with normal renal function.</description><subject>Aged</subject><subject>Bypass</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular diseases</subject><subject>Coronary artery</subject><subject>Coronary Artery Bypass - mortality</subject><subject>Coronary artery disease</subject><subject>Dialysis</subject><subject>Extracorporeal Circulation - mortality</subject><subject>Female</subject><subject>Germany - epidemiology</subject><subject>Heart diseases</subject><subject>Heart surgery</subject><subject>Hemodialysis</subject><subject>Humans</subject><subject>Kidney Failure, Chronic - mortality</subject><subject>Kidney Failure, Chronic - rehabilitation</subject><subject>Male</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>Patients</subject><subject>Prevalence</subject><subject>Renal Dialysis - mortality</subject><subject>Renal failure</subject><subject>Renal function</subject><subject>Retrospective Studies</subject><subject>Risk Assessment - methods</subject><subject>Risk Factors</subject><subject>Treatment Outcome</subject><issn>0300-5860</issn><issn>1861-0684</issn><issn>1435-1285</issn><issn>1861-0692</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkF1LwzAUhoMobk5_gDdSELyLnpM0aXopwy8YeKPXIU3TmdG1NWmR_XszNhC8euHwvC-Hh5BrhHsEKB4iAC8ZBRAUmJKUnZA55lxQZEqckjlwACqUhBm5iHEDgEUh-TmZoWQAueJzslr2oe9M2GVxCmuX0ndZ7U27iz7S2g2uq103ZoMZfcqY_fjxK0vHLI5m7bLgOtNmjfHtFNwlOWtMG93VMRfk8_npY_lKV-8vb8vHFbWsKEeKdS4arhSXRmDJoLbMcnS2UULxRhRGSVsioquxkkaVeVVZW7PGADcCSssX5O6wO4T-e3Jx1FsfrWtb07l-iloqKXguZAJv_4Gbfgrp46hZjkIUWDCRKDxQNvQxBtfoIfhtcqIR9F60PojWSbTei9YsdW6Oy1O1dfVf42iW_wIboniJ</recordid><startdate>200510</startdate><enddate>200510</enddate><creator>Tugtekin, S M</creator><creator>Alexiou, K</creator><creator>Georgi, Ch</creator><creator>Kappert, U</creator><creator>Knaut, M</creator><creator>Matschke, K</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7Z</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>200510</creationdate><title>Coronary surgery in dialysis-dependent patients with end stage renal failure</title><author>Tugtekin, S M ; Alexiou, K ; Georgi, Ch ; Kappert, U ; Knaut, M ; Matschke, K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c279t-1d45f38836a51920dc2c31ecf8583f57a86c9111ed1b6a894bbccd2fa03a509c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Bypass</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular diseases</topic><topic>Coronary artery</topic><topic>Coronary Artery Bypass - mortality</topic><topic>Coronary artery disease</topic><topic>Dialysis</topic><topic>Extracorporeal Circulation - mortality</topic><topic>Female</topic><topic>Germany - epidemiology</topic><topic>Heart diseases</topic><topic>Heart surgery</topic><topic>Hemodialysis</topic><topic>Humans</topic><topic>Kidney Failure, Chronic - mortality</topic><topic>Kidney Failure, Chronic - rehabilitation</topic><topic>Male</topic><topic>Morbidity</topic><topic>Mortality</topic><topic>Patients</topic><topic>Prevalence</topic><topic>Renal Dialysis - mortality</topic><topic>Renal failure</topic><topic>Renal function</topic><topic>Retrospective Studies</topic><topic>Risk Assessment - methods</topic><topic>Risk Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tugtekin, S M</creatorcontrib><creatorcontrib>Alexiou, K</creatorcontrib><creatorcontrib>Georgi, Ch</creatorcontrib><creatorcontrib>Kappert, U</creatorcontrib><creatorcontrib>Knaut, M</creatorcontrib><creatorcontrib>Matschke, K</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical research in cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tugtekin, S M</au><au>Alexiou, K</au><au>Georgi, Ch</au><au>Kappert, U</au><au>Knaut, M</au><au>Matschke, K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coronary surgery in dialysis-dependent patients with end stage renal failure</atitle><jtitle>Clinical research in cardiology</jtitle><addtitle>Z Kardiol</addtitle><date>2005-10</date><risdate>2005</risdate><volume>94</volume><issue>10</issue><spage>679</spage><epage>683</epage><pages>679-683</pages><issn>0300-5860</issn><issn>1861-0684</issn><eissn>1435-1285</eissn><eissn>1861-0692</eissn><abstract>The number of patients with dialysis-dependent end stage renal failure (ESRF) and coronary heart disease (CAD) has increased in recent years. Coronary artery bypass grafting (CABG) has become the standard treatment for CAD in this patient group, but is still considered as a risk procedure due to increased mortality and morbidity. In a retrospective study we analyzed our clinical results of isolated CABG in 40 dialysis-dependent patients with ESRF (5 female and 35 male, mean age 65+/-8.4 years) and the use of extracorporeal circulation. The perioperative control group comprised 51 patients (10 female and 41 male, mean age 67+/-7.3 years) with normal renal function and isolated CABG. Demographic and preoperative data were comparable in both groups. Hospital mortality was 2.5% in patients with ESRF and 0% in patients with normal renal function. Morbidity was comparable in both groups. The mean number of grafts was 3.1+/-0.9 in the dialysis group and 2.9+/-0.8 in the control group. In the follow-up of the dialysis group (34+/-23 months) 8 patients died. CABG in patients with dialysis-dependent ESRF can be performed with good clinical results and morbidity comparable to patients with normal renal function.</abstract><cop>Germany</cop><pub>Springer Nature B.V</pub><pmid>16200483</pmid><doi>10.1007/s00392-005-0286-2</doi><tpages>5</tpages></addata></record> |
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subjects | Aged Bypass Cardiovascular disease Cardiovascular diseases Coronary artery Coronary Artery Bypass - mortality Coronary artery disease Dialysis Extracorporeal Circulation - mortality Female Germany - epidemiology Heart diseases Heart surgery Hemodialysis Humans Kidney Failure, Chronic - mortality Kidney Failure, Chronic - rehabilitation Male Morbidity Mortality Patients Prevalence Renal Dialysis - mortality Renal failure Renal function Retrospective Studies Risk Assessment - methods Risk Factors Treatment Outcome |
title | Coronary surgery in dialysis-dependent patients with end stage renal failure |
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