Study on the Methods for Synthesis of GM-CSF Conjugates with Alendronic Acid

— In order to develop a target drug we studied the process of conjugation of recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) and alendronic acid (ALN). The conjugation reactions were performed both in solution and in the solid phase. The results of the examination of the...

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Veröffentlicht in:	Russian journal of bioorganic chemistry 2020-05, Vol.46 (3), p.342-348
Hauptverfasser:	Esina, T. I., Volosnikova, E. A., Lebedev, L. R., Kochneva, G. V., Grazhdantseva, A. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological properties Biomedical and Life Sciences Biomedical materials Biomedicine Bioorganic Chemistry Conjugates Conjugation Granulocyte-macrophage colony stimulating factor Hydroxyapatite Life Sciences Organic Chemistry Proteins Solid phases
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