Lizhong decoction ameliorates ulcerative colitis in mice via modulating gut microbiota and its metabolites

Ulcerative colitis (UC), a kind of inflammatory bowel disease, is generally characterized by chronic, persistent, relapsing, and nonspecific ulceration of the bowel, which is widespread in the world. Although the pathogenesis of UC is multifactorial, growing evidence has demonstrated that gut microb...

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Veröffentlicht in:	Applied microbiology and biotechnology 2020-07, Vol.104 (13), p.5999-6012
Hauptverfasser:	Zou, Junfeng, Shen, Yumeng, Chen, Mengjun, Zhang, Zhimiao, Xiao, Suwei, Liu, Chen, Wan, Yue, Yang, Lei, Jiang, Shu, Shang, Erxin, Qian, Dawei, Duan, Jinao
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Adenosine Analysis Animals Applied Microbial and Cell Physiology Bacteria Bacteria - classification Bacteria - drug effects Bacteria - isolation & purification Bacteria - metabolism Biomedical and Life Sciences Biotechnology Cholic acid Colitis, Ulcerative - chemically induced Colitis, Ulcerative - drug therapy Colitis, Ulcerative - metabolism Colitis, Ulcerative - microbiology Deoxycholic acid Dextran Sulfate - toxicity Digestive system Diseases Drugs, Chinese Herbal - administration & dosage Drugs, Chinese Herbal - pharmacology Feces - chemistry Feces - microbiology Flora Gastrointestinal Microbiome - drug effects Gastrointestinal tract Gene sequencing Herbal medicine Inflammation Inflammatory bowel disease Inflammatory bowel diseases Intestinal microflora Intestine Life Sciences Linolenic acid Linolenic acids Male Metabolism Metabolites Metabolome - drug effects Metabolomics Mice Mice, Inbred C57BL Microbial Genetics and Genomics Microbiology Microbiota Microbiota (Symbiotic organisms) Microorganisms Omega-3 fatty acids Opportunist infection Pathogenesis Probiotics Relapse RNA rRNA 16S Tryptophan Ulcerative colitis
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