Pediatric applications of Dotatate: early diagnostic and therapeutic experience
In recent years, new somatostatin receptor agents (SSTRs) have become available for diagnostic imaging and therapy in neuroendocrine tumors. The novel SSTR ligand DOTA-DPhel-Tyr3-octreotate (Dotatate) in particular can be linked with 68 Gallium for diagnostic imaging purposes, and with the β-emitter...
Gespeichert in:
| Veröffentlicht in: | Pediatric radiology 2020-06, Vol.50 (7), p.882-897 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 897 |
|---|---|
| container_issue | 7 |
| container_start_page | 882 |
| container_title | Pediatric radiology |
| container_volume | 50 |
| creator | McElroy, Kevin M. Binkovitz, Larry A. Trout, Andrew T. Czachowski, Michael R. Seghers, Victor J. Lteif, Aida N. States, Lisa J. |
| description | In recent years, new somatostatin receptor agents (SSTRs) have become available for diagnostic imaging and therapy in neuroendocrine tumors. The novel SSTR ligand DOTA-DPhel-Tyr3-octreotate (Dotatate) in particular can be linked with
68
Gallium for diagnostic imaging purposes, and with the β-emitter
177
Lutetium for radiotherapy in the setting of neuroendocrine tumors. Dotatate imaging offers distinct advantages in the evaluation of neuroendocrine tumors compared to standard techniques, including greater target-to-background ratio and lesion conspicuity, high sensitivity/specificity, improved spatial resolution with positron emission tomography (PET)/CT or PET/MR, and decreased radiation exposure. Although currently off-label in pediatrics, Dotatate theranostics in children are being explored, most notably in the setting of neuroblastoma and hereditary neuroendocrine syndromes. This article provides a multicenter case series of Dotatate imaging and therapy in pediatric patients in order to highlight the spectrum of potential clinical applications. |
| doi_str_mv | 10.1007/s00247-020-04688-z |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2411434105</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2411434105</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-d4628a35a727018c19f86150a5a5e187647751e987686ef1bcde1d0c4a10cc713</originalsourceid><addsrcrecordid>eNp9kE1PwzAMhiMEYmPwBzigSpwLdpM0LTc0PqVJ4wDnKEvd0WlrS9JJbL-ejA64IR_iyI9fSw9j5whXCKCuPUAiVAwJxCDSLIu3B2yIgicx5nl2yIbAAcNI5AN24v0CALhEfswGPBG5RJUO2fSFisp0rrKRadtlZU1XNbWPmjK6azoTim4iMm65iQI3rxvf7dC6iLp3cqal9e5Pny25impLp-yoNEtPZ_t3xN4e7l_HT_Fk-vg8vp3ElivZxYVIk8xwaVSiADOLeZmlKMFIIwkzlQqlJFIeuiylEme2ICzACoNgrUI-Ypd9buuajzX5Ti-atavDSZ0IDBIEggxU0lPWNd47KnXrqpVxG42gdw5171AHh_rbod6GpYt99Hq2ouJ35UdaAHgP-DCq5-T-bv8T-wUEzHyP</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2411434105</pqid></control><display><type>article</type><title>Pediatric applications of Dotatate: early diagnostic and therapeutic experience</title><source>MEDLINE</source><source>SpringerNature Complete Journals</source><creator>McElroy, Kevin M. ; Binkovitz, Larry A. ; Trout, Andrew T. ; Czachowski, Michael R. ; Seghers, Victor J. ; Lteif, Aida N. ; States, Lisa J.</creator><creatorcontrib>McElroy, Kevin M. ; Binkovitz, Larry A. ; Trout, Andrew T. ; Czachowski, Michael R. ; Seghers, Victor J. ; Lteif, Aida N. ; States, Lisa J.</creatorcontrib><description>In recent years, new somatostatin receptor agents (SSTRs) have become available for diagnostic imaging and therapy in neuroendocrine tumors. The novel SSTR ligand DOTA-DPhel-Tyr3-octreotate (Dotatate) in particular can be linked with
68
Gallium for diagnostic imaging purposes, and with the β-emitter
177
Lutetium for radiotherapy in the setting of neuroendocrine tumors. Dotatate imaging offers distinct advantages in the evaluation of neuroendocrine tumors compared to standard techniques, including greater target-to-background ratio and lesion conspicuity, high sensitivity/specificity, improved spatial resolution with positron emission tomography (PET)/CT or PET/MR, and decreased radiation exposure. Although currently off-label in pediatrics, Dotatate theranostics in children are being explored, most notably in the setting of neuroblastoma and hereditary neuroendocrine syndromes. This article provides a multicenter case series of Dotatate imaging and therapy in pediatric patients in order to highlight the spectrum of potential clinical applications.</description><identifier>ISSN: 0301-0449</identifier><identifier>EISSN: 1432-1998</identifier><identifier>DOI: 10.1007/s00247-020-04688-z</identifier><identifier>PMID: 32495176</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Child ; Computed tomography ; Conspicuity ; Contrast Media ; Diagnostic software ; Diagnostic systems ; Early experience ; Emitters ; Humans ; Imaging ; Medical diagnosis ; Medical imaging ; Medicine ; Medicine & Public Health ; Multimodal Imaging ; Neuroblastoma ; Neuroblastoma - diagnostic imaging ; Neuroblastoma - metabolism ; Neuroblastoma - radiotherapy ; Neuroendocrine tumors ; Neuroendocrine Tumors - diagnostic imaging ; Neuroendocrine Tumors - metabolism ; Neuroendocrine Tumors - radiotherapy ; Neuroradiology ; Nuclear Medicine ; Octreotide - analogs & derivatives ; Octreotide - therapeutic use ; Oncology ; Organometallic Compounds - therapeutic use ; Pediatrics ; Positron emission ; Positron emission tomography ; Precision medicine ; Radiation effects ; Radiation therapy ; Radiology ; Radiopharmaceuticals ; Receptors, Somatostatin - metabolism ; Review ; Sensitivity and Specificity ; Somatostatin ; Somatostatin receptors ; Spatial discrimination ; Spatial resolution ; Therapeutic applications ; Tomography ; Tumors ; Ultrasound</subject><ispartof>Pediatric radiology, 2020-06, Vol.50 (7), p.882-897</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020</rights><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-d4628a35a727018c19f86150a5a5e187647751e987686ef1bcde1d0c4a10cc713</citedby><cites>FETCH-LOGICAL-c375t-d4628a35a727018c19f86150a5a5e187647751e987686ef1bcde1d0c4a10cc713</cites><orcidid>0000-0002-3807-7455</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00247-020-04688-z$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00247-020-04688-z$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32495176$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>McElroy, Kevin M.</creatorcontrib><creatorcontrib>Binkovitz, Larry A.</creatorcontrib><creatorcontrib>Trout, Andrew T.</creatorcontrib><creatorcontrib>Czachowski, Michael R.</creatorcontrib><creatorcontrib>Seghers, Victor J.</creatorcontrib><creatorcontrib>Lteif, Aida N.</creatorcontrib><creatorcontrib>States, Lisa J.</creatorcontrib><title>Pediatric applications of Dotatate: early diagnostic and therapeutic experience</title><title>Pediatric radiology</title><addtitle>Pediatr Radiol</addtitle><addtitle>Pediatr Radiol</addtitle><description>In recent years, new somatostatin receptor agents (SSTRs) have become available for diagnostic imaging and therapy in neuroendocrine tumors. The novel SSTR ligand DOTA-DPhel-Tyr3-octreotate (Dotatate) in particular can be linked with
68
Gallium for diagnostic imaging purposes, and with the β-emitter
177
Lutetium for radiotherapy in the setting of neuroendocrine tumors. Dotatate imaging offers distinct advantages in the evaluation of neuroendocrine tumors compared to standard techniques, including greater target-to-background ratio and lesion conspicuity, high sensitivity/specificity, improved spatial resolution with positron emission tomography (PET)/CT or PET/MR, and decreased radiation exposure. Although currently off-label in pediatrics, Dotatate theranostics in children are being explored, most notably in the setting of neuroblastoma and hereditary neuroendocrine syndromes. This article provides a multicenter case series of Dotatate imaging and therapy in pediatric patients in order to highlight the spectrum of potential clinical applications.</description><subject>Child</subject><subject>Computed tomography</subject><subject>Conspicuity</subject><subject>Contrast Media</subject><subject>Diagnostic software</subject><subject>Diagnostic systems</subject><subject>Early experience</subject><subject>Emitters</subject><subject>Humans</subject><subject>Imaging</subject><subject>Medical diagnosis</subject><subject>Medical imaging</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Multimodal Imaging</subject><subject>Neuroblastoma</subject><subject>Neuroblastoma - diagnostic imaging</subject><subject>Neuroblastoma - metabolism</subject><subject>Neuroblastoma - radiotherapy</subject><subject>Neuroendocrine tumors</subject><subject>Neuroendocrine Tumors - diagnostic imaging</subject><subject>Neuroendocrine Tumors - metabolism</subject><subject>Neuroendocrine Tumors - radiotherapy</subject><subject>Neuroradiology</subject><subject>Nuclear Medicine</subject><subject>Octreotide - analogs & derivatives</subject><subject>Octreotide - therapeutic use</subject><subject>Oncology</subject><subject>Organometallic Compounds - therapeutic use</subject><subject>Pediatrics</subject><subject>Positron emission</subject><subject>Positron emission tomography</subject><subject>Precision medicine</subject><subject>Radiation effects</subject><subject>Radiation therapy</subject><subject>Radiology</subject><subject>Radiopharmaceuticals</subject><subject>Receptors, Somatostatin - metabolism</subject><subject>Review</subject><subject>Sensitivity and Specificity</subject><subject>Somatostatin</subject><subject>Somatostatin receptors</subject><subject>Spatial discrimination</subject><subject>Spatial resolution</subject><subject>Therapeutic applications</subject><subject>Tomography</subject><subject>Tumors</subject><subject>Ultrasound</subject><issn>0301-0449</issn><issn>1432-1998</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kE1PwzAMhiMEYmPwBzigSpwLdpM0LTc0PqVJ4wDnKEvd0WlrS9JJbL-ejA64IR_iyI9fSw9j5whXCKCuPUAiVAwJxCDSLIu3B2yIgicx5nl2yIbAAcNI5AN24v0CALhEfswGPBG5RJUO2fSFisp0rrKRadtlZU1XNbWPmjK6azoTim4iMm65iQI3rxvf7dC6iLp3cqal9e5Pny25impLp-yoNEtPZ_t3xN4e7l_HT_Fk-vg8vp3ElivZxYVIk8xwaVSiADOLeZmlKMFIIwkzlQqlJFIeuiylEme2ICzACoNgrUI-Ypd9buuajzX5Ti-atavDSZ0IDBIEggxU0lPWNd47KnXrqpVxG42gdw5171AHh_rbod6GpYt99Hq2ouJ35UdaAHgP-DCq5-T-bv8T-wUEzHyP</recordid><startdate>20200601</startdate><enddate>20200601</enddate><creator>McElroy, Kevin M.</creator><creator>Binkovitz, Larry A.</creator><creator>Trout, Andrew T.</creator><creator>Czachowski, Michael R.</creator><creator>Seghers, Victor J.</creator><creator>Lteif, Aida N.</creator><creator>States, Lisa J.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><orcidid>https://orcid.org/0000-0002-3807-7455</orcidid></search><sort><creationdate>20200601</creationdate><title>Pediatric applications of Dotatate: early diagnostic and therapeutic experience</title><author>McElroy, Kevin M. ; Binkovitz, Larry A. ; Trout, Andrew T. ; Czachowski, Michael R. ; Seghers, Victor J. ; Lteif, Aida N. ; States, Lisa J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-d4628a35a727018c19f86150a5a5e187647751e987686ef1bcde1d0c4a10cc713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Child</topic><topic>Computed tomography</topic><topic>Conspicuity</topic><topic>Contrast Media</topic><topic>Diagnostic software</topic><topic>Diagnostic systems</topic><topic>Early experience</topic><topic>Emitters</topic><topic>Humans</topic><topic>Imaging</topic><topic>Medical diagnosis</topic><topic>Medical imaging</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Multimodal Imaging</topic><topic>Neuroblastoma</topic><topic>Neuroblastoma - diagnostic imaging</topic><topic>Neuroblastoma - metabolism</topic><topic>Neuroblastoma - radiotherapy</topic><topic>Neuroendocrine tumors</topic><topic>Neuroendocrine Tumors - diagnostic imaging</topic><topic>Neuroendocrine Tumors - metabolism</topic><topic>Neuroendocrine Tumors - radiotherapy</topic><topic>Neuroradiology</topic><topic>Nuclear Medicine</topic><topic>Octreotide - analogs & derivatives</topic><topic>Octreotide - therapeutic use</topic><topic>Oncology</topic><topic>Organometallic Compounds - therapeutic use</topic><topic>Pediatrics</topic><topic>Positron emission</topic><topic>Positron emission tomography</topic><topic>Precision medicine</topic><topic>Radiation effects</topic><topic>Radiation therapy</topic><topic>Radiology</topic><topic>Radiopharmaceuticals</topic><topic>Receptors, Somatostatin - metabolism</topic><topic>Review</topic><topic>Sensitivity and Specificity</topic><topic>Somatostatin</topic><topic>Somatostatin receptors</topic><topic>Spatial discrimination</topic><topic>Spatial resolution</topic><topic>Therapeutic applications</topic><topic>Tomography</topic><topic>Tumors</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McElroy, Kevin M.</creatorcontrib><creatorcontrib>Binkovitz, Larry A.</creatorcontrib><creatorcontrib>Trout, Andrew T.</creatorcontrib><creatorcontrib>Czachowski, Michael R.</creatorcontrib><creatorcontrib>Seghers, Victor J.</creatorcontrib><creatorcontrib>Lteif, Aida N.</creatorcontrib><creatorcontrib>States, Lisa J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Pediatric radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McElroy, Kevin M.</au><au>Binkovitz, Larry A.</au><au>Trout, Andrew T.</au><au>Czachowski, Michael R.</au><au>Seghers, Victor J.</au><au>Lteif, Aida N.</au><au>States, Lisa J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pediatric applications of Dotatate: early diagnostic and therapeutic experience</atitle><jtitle>Pediatric radiology</jtitle><stitle>Pediatr Radiol</stitle><addtitle>Pediatr Radiol</addtitle><date>2020-06-01</date><risdate>2020</risdate><volume>50</volume><issue>7</issue><spage>882</spage><epage>897</epage><pages>882-897</pages><issn>0301-0449</issn><eissn>1432-1998</eissn><abstract>In recent years, new somatostatin receptor agents (SSTRs) have become available for diagnostic imaging and therapy in neuroendocrine tumors. The novel SSTR ligand DOTA-DPhel-Tyr3-octreotate (Dotatate) in particular can be linked with
68
Gallium for diagnostic imaging purposes, and with the β-emitter
177
Lutetium for radiotherapy in the setting of neuroendocrine tumors. Dotatate imaging offers distinct advantages in the evaluation of neuroendocrine tumors compared to standard techniques, including greater target-to-background ratio and lesion conspicuity, high sensitivity/specificity, improved spatial resolution with positron emission tomography (PET)/CT or PET/MR, and decreased radiation exposure. Although currently off-label in pediatrics, Dotatate theranostics in children are being explored, most notably in the setting of neuroblastoma and hereditary neuroendocrine syndromes. This article provides a multicenter case series of Dotatate imaging and therapy in pediatric patients in order to highlight the spectrum of potential clinical applications.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>32495176</pmid><doi>10.1007/s00247-020-04688-z</doi><tpages>16</tpages><orcidid>https://orcid.org/0000-0002-3807-7455</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0301-0449 |
| ispartof | Pediatric radiology, 2020-06, Vol.50 (7), p.882-897 |
| issn | 0301-0449 1432-1998 |
| language | eng |
| recordid | cdi_proquest_journals_2411434105 |
| source | MEDLINE; SpringerNature Complete Journals |
| subjects | Child Computed tomography Conspicuity Contrast Media Diagnostic software Diagnostic systems Early experience Emitters Humans Imaging Medical diagnosis Medical imaging Medicine Medicine & Public Health Multimodal Imaging Neuroblastoma Neuroblastoma - diagnostic imaging Neuroblastoma - metabolism Neuroblastoma - radiotherapy Neuroendocrine tumors Neuroendocrine Tumors - diagnostic imaging Neuroendocrine Tumors - metabolism Neuroendocrine Tumors - radiotherapy Neuroradiology Nuclear Medicine Octreotide - analogs & derivatives Octreotide - therapeutic use Oncology Organometallic Compounds - therapeutic use Pediatrics Positron emission Positron emission tomography Precision medicine Radiation effects Radiation therapy Radiology Radiopharmaceuticals Receptors, Somatostatin - metabolism Review Sensitivity and Specificity Somatostatin Somatostatin receptors Spatial discrimination Spatial resolution Therapeutic applications Tomography Tumors Ultrasound |
| title | Pediatric applications of Dotatate: early diagnostic and therapeutic experience |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T05%3A02%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pediatric%20applications%20of%20Dotatate:%20early%20diagnostic%20and%20therapeutic%20experience&rft.jtitle=Pediatric%20radiology&rft.au=McElroy,%20Kevin%20M.&rft.date=2020-06-01&rft.volume=50&rft.issue=7&rft.spage=882&rft.epage=897&rft.pages=882-897&rft.issn=0301-0449&rft.eissn=1432-1998&rft_id=info:doi/10.1007/s00247-020-04688-z&rft_dat=%3Cproquest_cross%3E2411434105%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2411434105&rft_id=info:pmid/32495176&rfr_iscdi=true |