Primary analysis of JUMP, a phase 3b, expanded‐access study evaluating the safety and efficacy of ruxolitinib in patients with myelofibrosis, including those with low platelet counts

Summary Ruxolitinib is a potent Janus kinase (JAK) 1/JAK2 inhibitor approved for the treatment of myelofibrosis (MF). Ruxolitinib was assessed in JUMP, a large (N = 2233), phase 3b, expanded‐access study in MF in countries without access to ruxolitinib outside a clinical trial, which included patien...

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Veröffentlicht in:British journal of haematology 2020-06, Vol.189 (5), p.888-903
Hauptverfasser: Al‐Ali, Haifa Kathrin, Griesshammer, Martin, Foltz, Lynda, Palumbo, Giuseppe A., Martino, Bruno, Palandri, Francesca, Liberati, Anna Marina, Coutre, Philipp, García‐Hernández, Carmen, Zaritskey, Andrey, Tavares, Renato, Gupta, Vikas, Raanani, Pia, Giraldo, Pilar, Hänel, Mathias, Damiani, Daniela, Sacha, Tomasz, Bouard, Catherine, Paley, Carole, Tiwari, Ranjan, Mannelli, Francesco, Vannucchi, Alessandro M.
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Sprache:eng
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