Pharmacokinetics of an intravenous bolus dose of clonidine in children undergoing surgery

Background Clonidine is used off‐label in children but only limited pediatric pharmacokinetic data are available for intravenously administered clonidine. Objectives To determine pharmacokinetic parameter estimates of clonidine in healthy children undergoing surgery and to investigate age‐related di...

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Veröffentlicht in:	Pediatric anesthesia 2020-05, Vol.30 (5), p.607-613
Hauptverfasser:	Nielsen, Bettina N., Anderson, Brian J., Falcon, Lars, Henneberg, Steen W., Lauritsen, Torsten, Lomstein, Erik, Ydemann, Mogens, Afshari, Arash, Goobie, Susan
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Analgesics - administration & dosage Analgesics - pharmacokinetics Child, Preschool children clonidine Clonidine - administration & dosage Clonidine - pharmacokinetics Female Heart surgery Humans Infant Injections, Intravenous Male Pharmacokinetics surgery Surgical Procedures, Operative
Online-Zugang:	Volltext
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