Human Amnion Membrane Proteins Prevent Doxorubicin-Induced Oxidative Stress Injury and Apoptosis in Rat H9c2 Cardiomyocytes

Doxorubicin (DOX) is widely used as an effective chemotherapy agent in cancer treatment. Cardiac toxicity in cancer treatment with DOX demand urgent attention and no effective treatment has been established for DOX-induced cardiomyopathy. It has been well documented that human amniotic membrane prot...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cardiovascular toxicology 2020-08, Vol.20 (4), p.370-379
Hauptverfasser:	Faridvand, Yousef, Haddadi, Parinaz, Vahedian, Vahid, Nozari, Samira, Nejabati, Hamid Reza, Pezeshkian, Masoud, Afrasiabi, Abbas, Safaie, Nasser, Jodati, Ahmadreza, Nouri, Mohammad
Format:	Artikel
Sprache:	eng
Schlagworte:	Amnion Amnion - chemistry Amniotic membrane Animals Annexin V Antibiotics, Antineoplastic - toxicity Antioxidants Antioxidants - isolation & purification Antioxidants - pharmacology Apoptosis Apoptosis - drug effects Apoptosis Regulatory Proteins - metabolism BAX protein Bcl-2 protein Biomedical and Life Sciences Biomedicine Calcium (intracellular) Calcium ions Calcium Signaling - drug effects Cancer Cancer therapies Cardiology Cardiomyocytes Cardiomyopathy Cardiotoxicity Catalase Cell injury Cell Line Chemical compounds Chemotherapy Deoxyribonucleic acid DNA Doxorubicin Doxorubicin - toxicity Flow cytometry Gene expression Heart cells Heart Diseases - chemically induced Heart Diseases - metabolism Heart Diseases - pathology Heart Diseases - prevention & control Humans Injury prevention Malondialdehyde Membrane potential Membrane Potential, Mitochondrial - drug effects Membrane proteins Membrane Proteins - isolation & purification Membrane Proteins - pharmacology Membranes Mitochondria Mitochondria, Heart - drug effects Mitochondria, Heart - metabolism Mitochondria, Heart - pathology Mitochondrial Proteins - metabolism Myocytes, Cardiac - drug effects Myocytes, Cardiac - metabolism Myocytes, Cardiac - pathology NF-κB protein Oxidative stress Oxidative Stress - drug effects p53 Protein Pharmacology Pharmacology/Toxicology Proteins Rats Reactive oxygen species Reactive Oxygen Species - metabolism Superoxide Superoxide dismutase Toxicity Tumor proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!