New type platforms for in vitro vaccine assembly
Studying the structure of plant viruses and viral coat proteins along with the possibilities of their modification and structural remodeling is very important for the development of novel approaches to the design of biotechnological products, including those of medical use. Being nonpathogenic for m...
Gespeichert in:
| Veröffentlicht in: | Moscow University biological sciences bulletin 2015, Vol.70 (4), p.177-183 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 183 |
|---|---|
| container_issue | 4 |
| container_start_page | 177 |
| container_title | Moscow University biological sciences bulletin |
| container_volume | 70 |
| creator | Atabekov, J. G Nikitin, N. A Karpova, O. V |
| description | Studying the structure of plant viruses and viral coat proteins along with the possibilities of their modification and structural remodeling is very important for the development of novel approaches to the design of biotechnological products, including those of medical use. Being nonpathogenic for mammals, in particular for humans, undoubtedly, make plant viruses advantageous for the development of new functional and biologically active materials, particularly, candidate vaccines. The present review focuses attention on characteristics and applying in biotechnology of spherical particles—the new type platforms generated by structural remodeling of plant viruses. Spherical particles do not have structural analogues among the icosahedral viruses and represent a new type of biogenic platforms. The assembly of the spherical particle–antigen immunogenic complexes in vitro bring in the possibilities of inexpensive and easy production of different vaccines. |
| doi_str_mv | 10.3103/S0096392515040045 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2404396966</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2404396966</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2555-168ed079895ac0c60f8f38815d197c5682217632a69518b5043b86b121d83aec3</originalsourceid><addsrcrecordid>eNp9kEFLAzEQhYMoWKs_wJMBz6szySabHKVoFYoeasFbyKbZsqXdXZNtpf_elBU8CF5mDu97b4ZHyDXCHUfg93MALblmAgXkALk4ISPUPM8KjR-nZHSUs6N-Ti5iXAMIobkeEXj1X7Q_dJ52G9tXbdhGmiatG7qv-9DSvXWubjy1MfptuTlckrPKbqK_-tljsnh6fJ88Z7O36cvkYZY5JoTIUCq_hEIrLawDJ6FSFVcKxRJ14YRUjGEhObNSC1RlepqXSpbIcKm49Y6Pye2Q24X2c-djb9btLjTppGF5orXUUiYKB8qFNsbgK9OFemvDwSCYYzHmTzHJwwZPTGyz8uE3-T_TzWCqbGvsKtTRLOYMUAJAobQu-Ddnzmrl</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2404396966</pqid></control><display><type>article</type><title>New type platforms for in vitro vaccine assembly</title><source>SpringerLink Journals</source><creator>Atabekov, J. G ; Nikitin, N. A ; Karpova, O. V</creator><creatorcontrib>Atabekov, J. G ; Nikitin, N. A ; Karpova, O. V</creatorcontrib><description>Studying the structure of plant viruses and viral coat proteins along with the possibilities of their modification and structural remodeling is very important for the development of novel approaches to the design of biotechnological products, including those of medical use. Being nonpathogenic for mammals, in particular for humans, undoubtedly, make plant viruses advantageous for the development of new functional and biologically active materials, particularly, candidate vaccines. The present review focuses attention on characteristics and applying in biotechnology of spherical particles—the new type platforms generated by structural remodeling of plant viruses. Spherical particles do not have structural analogues among the icosahedral viruses and represent a new type of biogenic platforms. The assembly of the spherical particle–antigen immunogenic complexes in vitro bring in the possibilities of inexpensive and easy production of different vaccines.</description><identifier>ISSN: 0096-3925</identifier><identifier>EISSN: 1934-791X</identifier><identifier>DOI: 10.3103/S0096392515040045</identifier><language>eng</language><publisher>New York: Allerton Press</publisher><subject>Biochemistry ; Biological activity ; Biomedical and Life Sciences ; Biotechnology ; Cell Biology ; coat proteins ; humans ; Immunogenicity ; Life Sciences ; Plant Sciences ; Plant viruses ; Vaccines ; Virology ; viruses ; Zoology</subject><ispartof>Moscow University biological sciences bulletin, 2015, Vol.70 (4), p.177-183</ispartof><rights>Allerton Press, Inc. 2015</rights><rights>Allerton Press, Inc. 2015.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2555-168ed079895ac0c60f8f38815d197c5682217632a69518b5043b86b121d83aec3</citedby><cites>FETCH-LOGICAL-c2555-168ed079895ac0c60f8f38815d197c5682217632a69518b5043b86b121d83aec3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.3103/S0096392515040045$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.3103/S0096392515040045$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids></links><search><creatorcontrib>Atabekov, J. G</creatorcontrib><creatorcontrib>Nikitin, N. A</creatorcontrib><creatorcontrib>Karpova, O. V</creatorcontrib><title>New type platforms for in vitro vaccine assembly</title><title>Moscow University biological sciences bulletin</title><addtitle>Moscow Univ. Biol.Sci. Bull</addtitle><description>Studying the structure of plant viruses and viral coat proteins along with the possibilities of their modification and structural remodeling is very important for the development of novel approaches to the design of biotechnological products, including those of medical use. Being nonpathogenic for mammals, in particular for humans, undoubtedly, make plant viruses advantageous for the development of new functional and biologically active materials, particularly, candidate vaccines. The present review focuses attention on characteristics and applying in biotechnology of spherical particles—the new type platforms generated by structural remodeling of plant viruses. Spherical particles do not have structural analogues among the icosahedral viruses and represent a new type of biogenic platforms. The assembly of the spherical particle–antigen immunogenic complexes in vitro bring in the possibilities of inexpensive and easy production of different vaccines.</description><subject>Biochemistry</subject><subject>Biological activity</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Cell Biology</subject><subject>coat proteins</subject><subject>humans</subject><subject>Immunogenicity</subject><subject>Life Sciences</subject><subject>Plant Sciences</subject><subject>Plant viruses</subject><subject>Vaccines</subject><subject>Virology</subject><subject>viruses</subject><subject>Zoology</subject><issn>0096-3925</issn><issn>1934-791X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp9kEFLAzEQhYMoWKs_wJMBz6szySabHKVoFYoeasFbyKbZsqXdXZNtpf_elBU8CF5mDu97b4ZHyDXCHUfg93MALblmAgXkALk4ISPUPM8KjR-nZHSUs6N-Ti5iXAMIobkeEXj1X7Q_dJ52G9tXbdhGmiatG7qv-9DSvXWubjy1MfptuTlckrPKbqK_-tljsnh6fJ88Z7O36cvkYZY5JoTIUCq_hEIrLawDJ6FSFVcKxRJ14YRUjGEhObNSC1RlepqXSpbIcKm49Y6Pye2Q24X2c-djb9btLjTppGF5orXUUiYKB8qFNsbgK9OFemvDwSCYYzHmTzHJwwZPTGyz8uE3-T_TzWCqbGvsKtTRLOYMUAJAobQu-Ddnzmrl</recordid><startdate>2015</startdate><enddate>2015</enddate><creator>Atabekov, J. G</creator><creator>Nikitin, N. A</creator><creator>Karpova, O. V</creator><general>Allerton Press</general><general>Springer Nature B.V</general><scope>FBQ</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>2015</creationdate><title>New type platforms for in vitro vaccine assembly</title><author>Atabekov, J. G ; Nikitin, N. A ; Karpova, O. V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2555-168ed079895ac0c60f8f38815d197c5682217632a69518b5043b86b121d83aec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Biochemistry</topic><topic>Biological activity</topic><topic>Biomedical and Life Sciences</topic><topic>Biotechnology</topic><topic>Cell Biology</topic><topic>coat proteins</topic><topic>humans</topic><topic>Immunogenicity</topic><topic>Life Sciences</topic><topic>Plant Sciences</topic><topic>Plant viruses</topic><topic>Vaccines</topic><topic>Virology</topic><topic>viruses</topic><topic>Zoology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Atabekov, J. G</creatorcontrib><creatorcontrib>Nikitin, N. A</creatorcontrib><creatorcontrib>Karpova, O. V</creatorcontrib><collection>AGRIS</collection><collection>CrossRef</collection><jtitle>Moscow University biological sciences bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Atabekov, J. G</au><au>Nikitin, N. A</au><au>Karpova, O. V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New type platforms for in vitro vaccine assembly</atitle><jtitle>Moscow University biological sciences bulletin</jtitle><stitle>Moscow Univ. Biol.Sci. Bull</stitle><date>2015</date><risdate>2015</risdate><volume>70</volume><issue>4</issue><spage>177</spage><epage>183</epage><pages>177-183</pages><issn>0096-3925</issn><eissn>1934-791X</eissn><abstract>Studying the structure of plant viruses and viral coat proteins along with the possibilities of their modification and structural remodeling is very important for the development of novel approaches to the design of biotechnological products, including those of medical use. Being nonpathogenic for mammals, in particular for humans, undoubtedly, make plant viruses advantageous for the development of new functional and biologically active materials, particularly, candidate vaccines. The present review focuses attention on characteristics and applying in biotechnology of spherical particles—the new type platforms generated by structural remodeling of plant viruses. Spherical particles do not have structural analogues among the icosahedral viruses and represent a new type of biogenic platforms. The assembly of the spherical particle–antigen immunogenic complexes in vitro bring in the possibilities of inexpensive and easy production of different vaccines.</abstract><cop>New York</cop><pub>Allerton Press</pub><doi>10.3103/S0096392515040045</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0096-3925 |
| ispartof | Moscow University biological sciences bulletin, 2015, Vol.70 (4), p.177-183 |
| issn | 0096-3925 1934-791X |
| language | eng |
| recordid | cdi_proquest_journals_2404396966 |
| source | SpringerLink Journals |
| subjects | Biochemistry Biological activity Biomedical and Life Sciences Biotechnology Cell Biology coat proteins humans Immunogenicity Life Sciences Plant Sciences Plant viruses Vaccines Virology viruses Zoology |
| title | New type platforms for in vitro vaccine assembly |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T06%3A51%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=New%20type%20platforms%20for%20in%20vitro%20vaccine%20assembly&rft.jtitle=Moscow%20University%20biological%20sciences%20bulletin&rft.au=Atabekov,%20J.%20G&rft.date=2015&rft.volume=70&rft.issue=4&rft.spage=177&rft.epage=183&rft.pages=177-183&rft.issn=0096-3925&rft.eissn=1934-791X&rft_id=info:doi/10.3103/S0096392515040045&rft_dat=%3Cproquest_cross%3E2404396966%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2404396966&rft_id=info:pmid/&rfr_iscdi=true |