A portable electrochemiluminescence bipolar electrode array for the visualized sensing of Cas9 activity

CRISPR/Cas9 has become a powerful tool for genomic manipulation, and the evaluation of the Cas9 activity is essential for the precise control of the CRISPR system. Herein, we develop a point-of-care platform for the rapid and visible determination of the Cas9 activity. A bipolar electrochemiluminesc...

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Veröffentlicht in:	Analyst (London) 2020-05, Vol.145 (1), p.3569-3574
Hauptverfasser:	Guo, Rui, Hu, Shanwen, Wang, Zonghua
Format:	Artikel
Sprache:	eng
Schlagworte:	Anodizing Base Sequence Biosensing Techniques - instrumentation Biosensors Circuits CRISPR CRISPR-Associated Protein 9 - metabolism Deoxyribonucleic acid DNA DNA Probes - genetics DNA Probes - metabolism Electrochemiluminescence Electrochemistry Electrodes Glass substrates Luminescent Measurements Oxidation Poles Polydimethylsiloxane Silicone resins
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