Efficient synthesis of new 3-amino-4-cyanothiophene derivatives

An efficient and atom economic modification of a previously reported synthetic pathway to tetrasubstituted thiophenes is described. The previously published synthetic methodology involved a one pot procedure starting with ketene dithioacetal and an appropriate secondary amine, and subsequent reactio...

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Veröffentlicht in:	Chemical papers 2020-08, Vol.74 (8), p.2491-2500
Hauptverfasser:	El-Meligie, Salwa E. M., Khalil, Nadia A., El-Nassan, Hala B., Ibraheem, Ahmed A. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biotechnology Chemistry Chemistry and Materials Science Chemistry/Food Science Derivatives Equivalence Industrial Chemistry/Chemical Engineering Materials Science Medicinal Chemistry Original Paper Reagents Sodium sulfide Thiophenes
Online-Zugang:	Volltext
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