Virtual Screening Based on Pharmacophore to Discover Host ER Alpha-Glucosidase II Inhibitor for Dengue Therapy

Dengue is one of the crucial diseases in human-caused by dengue virus (DENV) infection. However, the development of DENV antiviral is often facing a problem because no effective drug to treat infection caused by all DENV serotypes. The inhibition of host protein involved in DENV life cycle can be a...

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Veröffentlicht in:	Key engineering materials 2020-04, Vol.840, p.221-229
Hauptverfasser:	Ariavianti, Elsafira, Stephanie, filia, Tambunan, Usman Sumo Friend
Format:	Artikel
Sprache:	eng
Schlagworte:	Endoplasmic reticulum Glucosidase Glycoproteins Lead compounds Ligands Molecular docking Natural products Pharmacology Proteins Screening Simulation Software Toxicity Viruses
Online-Zugang:	Volltext
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