A novel peptide targeting gastrin releasing peptide receptor for pancreatic neoplasm detection

Pancreatic cancer has a high mortality rate and efforts towards diagnosis and therapy at an early stage are particularly appealing. Recently, a small peptide, BBN 7-14 , has attracted much attention for its specific binding ability to gastrin releasing peptide receptor (GRPR), which is highly overex...

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Veröffentlicht in:	Biomaterials science 2020-05, Vol.8 (9), p.2682-2693
Hauptverfasser:	Tu, Yuanbiao, Tao, Ji, Wang, Fang, Liu, Peifei, Han, Zhihao, Li, Zhaolun, Ma, Yi, Gu, Yueqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Animals Binding Cancer Cell Line, Tumor Diagnosis Female Fluorescence Fluorescent Dyes - administration & dosage Fluorescent Dyes - pharmacokinetics Humans Male Medical imaging Mice, Nude Optical Imaging Pancreatic cancer Pancreatic Neoplasms - diagnostic imaging Pancreatic Neoplasms - metabolism Peptides Peptides - administration & dosage Peptides - pharmacokinetics Radioisotopes Radiopharmaceuticals - administration & dosage Radiopharmaceuticals - pharmacokinetics Receptors Receptors, Bombesin - metabolism Single Photon Emission Computed Tomography Computed Tomography Stability Technetium - administration & dosage Technetium - pharmacokinetics
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