High-Throughput Platform to Identify Antibody Conjugation Sites from Antibody–Drug Conjugate Libraries

Antibody–drug conjugates (ADCs) are a therapeutic modality that traditionally enable the targeted delivery of highly potent cytotoxic agents to specific cells such as tumor cells. More recently, antibodies have been used to deliver molecules such as antibiotics, antigens, and adjuvants to bacteria o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bioconjugate chemistry 2020-04, Vol.31 (4), p.1199-1208
Hauptverfasser: Yamazoe, Sayumi, Hogan, Jason M, West, Sean M, Deng, Xiaodi A, Kotapati, Srikanth, Shao, Xiang, Holder, Patrick, Lamba, Vandana, Huber, Mary, Qiang, Cong, Gangwar, Sanjeev, Rao, Chetana, Dollinger, Gavin, Rajpal, Arvind, Strop, Pavel
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!