Safety and efficacy of tocilizumab as monotherapy or in combination with methotrexate in Tunisian patients with active rheumatoid arthritis and inadequate response to disease-modifying anti-rheumatic drugs in conditions close to clinical practice

Objectives We aimed to assess the safety and efficacy of tocilizumab as monotherapy or in combination with methotrexate in a routine clinical practice setting in Tunisian patients with RA who did not respond to conventional treatment with disease-modifying anti-rheumatic drugs (DMARDs-IR). Method A...

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Veröffentlicht in:	Clinical rheumatology 2020-05, Vol.39 (5), p.1449-1455
Hauptverfasser:	Bouajina, Elyes, Zakraoui, Leith, Kchir, Montassar, Kochbati, Samir, Baklouti, Sofiene
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies, Monoclonal, Humanized - adverse effects Antibodies, Monoclonal, Humanized - therapeutic use Antirheumatic Agents - adverse effects Antirheumatic Agents - therapeutic use Arthritis, Rheumatoid - drug therapy Clinical medicine Clinical trials Drug Administration Schedule Drug Therapy, Combination Female Humans Hypercholesterolemia Immunosuppressive agents Male Medicine Medicine & Public Health Methotrexate Methotrexate - adverse effects Methotrexate - therapeutic use Middle Aged Monoclonal antibodies Neutropenia Original Article Patients Remission Rheumatoid arthritis Rheumatology Safety Treatment Outcome Triglycerides Tumor necrosis factor Tumor necrosis factor-TNF Tumors Tunisia
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