Identification of Key Genes Related to Lung Squamous Cell Carcinoma Using Bioinformatics Analysis

Lung squamous cell carcinoma (LUSC) is often diagnosed at the advanced stage with poor prognosis. The mechanisms of its pathogenesis and prognosis require urgent elucidation. This study was performed to screen potential biomarkers related to the occurrence, development and prognosis of LUSC to revea...

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Veröffentlicht in:	International journal of molecular sciences 2020-04, Vol.21 (8), p.2994, Article 2994
Hauptverfasser:	Gao, Miaomiao, Kong, Weikaixin, Huang, Zhuo, Xie, Zhengwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry & Molecular Biology Bioinformatics Biomarkers Biomarkers, Tumor Cancer therapies Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - mortality Cell cycle Cell division Chemistry Chemistry, Multidisciplinary Chemotherapy Computational Biology - methods Databases, Nucleic Acid Datasets DNA microarrays FEN1 protein Gene expression Gene Expression Profiling Genes Genomes Humans Immunotherapy Kinases Life Sciences & Biomedicine Lung cancer Lung carcinoma Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - mortality lung squamous carcinoma Lungs Medical prognosis Model accuracy Network analysis Pathogenesis Physical Sciences Prognosis Proportional Hazards Models Protein Interaction Mapping Protein Interaction Maps Proteins Regression analysis Reproducibility of Results ROC Curve Science & Technology Squamous cell carcinoma Survival Survival analysis Transcriptome
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