Cu-Catalyzed three-component coupling reactions using nitriles, 1,3-dienes and silylboranes

This paper reports novel Cu-catalyzed three-component coupling reactions using nitriles, 1,3-dienes and silylboranes. The desired reactions proceed at room temperature and yield β,γ-unsaturated ketones with a (dimethylphenylsilyl)methyl moiety at the α-position. Diverse nitriles participate in the r...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2020-04, Vol.56 (34), p.4648-4651
Hauptverfasser:	Matsuda, Yuki, Tsuji, Yasushi, Fujihara, Tetsuaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical reactions Coupling Dienes Ketones Nitriles Regioselectivity Room temperature
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container_title	Chemical communications (Cambridge, England)
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creator	Matsuda, Yuki Tsuji, Yasushi Fujihara, Tetsuaki
description	This paper reports novel Cu-catalyzed three-component coupling reactions using nitriles, 1,3-dienes and silylboranes. The desired reactions proceed at room temperature and yield β,γ-unsaturated ketones with a (dimethylphenylsilyl)methyl moiety at the α-position. Diverse nitriles participate in the reaction and the corresponding products were obtained in good to high yields with high regioselectivity. Novel Cu-catalyzed three-component coupling reactions using nitriles, 1,3-dienes and silylboranes have been achieved. The desired reactions proceed at room temperature and yield β,γ-unsaturated ketones.
doi_str_mv	10.1039/d0cc01803a
format	Article
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The desired reactions proceed at room temperature and yield β,γ-unsaturated ketones with a (dimethylphenylsilyl)methyl moiety at the α-position. Diverse nitriles participate in the reaction and the corresponding products were obtained in good to high yields with high regioselectivity. Novel Cu-catalyzed three-component coupling reactions using nitriles, 1,3-dienes and silylboranes have been achieved. 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source	Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects	Chemical reactions Coupling Dienes Ketones Nitriles Regioselectivity Room temperature
title	Cu-Catalyzed three-component coupling reactions using nitriles, 1,3-dienes and silylboranes
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