Antineoplastic Agents: Environmental Prevalence and Adverse Outcomes in Aquatic Organisms

Cancer is the second leading cause of death worldwide, with 9.6 million cancer‐related deaths in 2018. Cancer incidence has increased over time, and so has the prescription rate of chemotherapeutic drugs. These pharmaceuticals, known as antineoplastic agents, enter the aquatic environment via human...

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Veröffentlicht in:	Environmental toxicology and chemistry 2020-05, Vol.39 (5), p.967-985
Hauptverfasser:	Wormington, Alexis M., De María, Maite, Kurita, Hajime G., Bisesi, Joseph H., Denslow, Nancy D., Martyniuk, Christopher J.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Fluorouracil Alkylating agents Alkylation Antimetabolites Antineoplastic drugs Aquatic environment Aquatic organisms Aquatic toxicology Cancer Contaminants of emerging concern Cyclophosphamide Drugs Human wastes Ifosfamide Immunotoxicity Literature reviews Methotrexate Mode of action Pharmaceuticals Risk Surface water Tamoxifen Toxicity Wastewater treatment
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