Correction of both immunodeficiency and hypoparathyroidism by thymus transplantation in complete DiGeorge syndrome

Combined immune deficiency due to athymia in patients with complete DiGeorge syndrome can be corrected by allogeneic thymus transplantation. Hypoparathyroidism is a frequent concomitant clinical problem in these patients, which persists after thymus transplantation. Cotransplantation of allogeneic t...

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Veröffentlicht in:	American journal of transplantation 2020-05, Vol.20 (5), p.1447-1450
Hauptverfasser:	Kreins, Alexandra Y., Junghanns, Florence, Mifsud, William, Somana, Kathy, Sebire, Neil, Rampling, Dyanne, Worth, Austen, Sirin, Methap, Schuetz, Catharina, Schulz, Ansgar, Hoenig, Manfred, Thrasher, Adrian J., Davies, Edward G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy Case reports clinical research/practice DiGeorge Syndrome - complications DiGeorge Syndrome - surgery endocrinology/diabetology Fluorescence in situ hybridization Graft rejection Histocompatibility antigen HLA Humans Hypoparathyroidism immune deficiency Immune system Immune Tolerance immunobiology Immunodeficiency Immunologic Deficiency Syndromes Immunological tolerance In Situ Hybridization, Fluorescence major histocompatibility complex Parathyroid Patients Thymic hypoplasia Thymus Thymus Gland thymus/thymic biology tolerance: mechanisms translational research/science Transplantation Transplantation, Homologous Transplants & implants
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