Acitretin-induced differentiation syndrome in a case of generalized pustular psoriasis
Arterial blood gas analysis showed respiratory alkalosis with metabolic acidosis, however, renal function test and serum electrolytes were normal. Differentiation syndrome is seen in 2–27% of acute promyelocytic leukemia patients on all trans retinoic acid, with 5% mortality. [1] Diagnosis is based...
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| Veröffentlicht in: | Indian journal of dermatology, venereology, and leprology venereology, and leprology, 2020-03, Vol.86 (2), p.231-231 |
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| container_title | Indian journal of dermatology, venereology, and leprology |
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| creator | Gowda, Priyanka Shastry, Veeranna Ranugha, P. S. S. Rangappa, Vinutha |
| description | Arterial blood gas analysis showed respiratory alkalosis with metabolic acidosis, however, renal function test and serum electrolytes were normal. Differentiation syndrome is seen in 2–27% of acute promyelocytic leukemia patients on all trans retinoic acid, with 5% mortality. [1] Diagnosis is based on the presence of at least two of the following signs and symptoms: dyspnea, unexplained fever, weight gain >5 kg, unexplained hypotension, acute renal failure and chest radiograph demonstrating pulmonary infiltrates or pleuro-pericardial effusion. |
| doi_str_mv | 10.4103/ijdvl.IJDVL_318_18 |
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| ispartof | Indian journal of dermatology, venereology, and leprology, 2020-03, Vol.86 (2), p.231-231 |
| issn | 0378-6323 0973-3922 1998-3611 |
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| source | MEDLINE; Bioline International; EZB-FREE-00999 freely available EZB journals |
| subjects | Abdomen Acids Acitretin Acitretin - adverse effects Acute myelocytic leukemia Adult Care and treatment Case reports Cyclosporins Dyspnea Edema Female Fever Glucocorticoids Humans Keratolytic Agents - adverse effects Leukemia Mortality Pathogenesis Patients Prednisolone Psoriasis Psoriasis - chemically induced Psoriasis - diagnosis Respiratory distress syndrome Retinoids Skin Diseases, Vesiculobullous - chemically induced Skin Diseases, Vesiculobullous - diagnosis Tretinoin |
| title | Acitretin-induced differentiation syndrome in a case of generalized pustular psoriasis |
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