Sevoflurane Post-treatment Upregulated miR-203 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuroinflammation by Targeting MyD88

To investigate the expression of miR-203 by sevoflurane treatment and its effect on neuroinflammation induced by cerebral ischemia-reperfusion. Rats were randomly divided into sham operation group (C), cerebral ischemia-reperfusion group (I/R), and sevoflurane treatment group (S). The neurological f...

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Veröffentlicht in:	Inflammation 2020-04, Vol.43 (2), p.651-663
Hauptverfasser:	Zhong, Huagen, Chen, Hui, Gu, Changwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Agonists Animals Apoptosis Biomedical and Life Sciences Biomedicine Brain Ischemia - genetics Brain Ischemia - metabolism Brain Ischemia - prevention & control Cerebral infarction Drug Delivery Systems - methods Enzyme-linked immunosorbent assay Gene Expression Immunology Inflammation Inflammation - metabolism Inflammation - prevention & control Internal Medicine Ischemia Male MicroRNAs - biosynthesis MicroRNAs - genetics mRNA MyD88 protein Myeloid Differentiation Factor 88 - antagonists & inhibitors Myeloid Differentiation Factor 88 - biosynthesis Myeloid Differentiation Factor 88 - genetics Original Article Pathology Pharmacology/Toxicology Platelet Aggregation Inhibitors - administration & dosage Polymerase chain reaction Random Allocation Rats Rats, Sprague-Dawley Reperfusion Reperfusion Injury - genetics Reperfusion Injury - metabolism Reperfusion Injury - prevention & control Rheumatology Sevoflurane Sevoflurane - administration & dosage Up-Regulation - drug effects Up-Regulation - physiology
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