Mitochondria-Modulating Porous Se@SiO2 Nanoparticles Provide Resistance to Oxidative Injury in Airway Epithelial Cells: Implications for Acute Lung Injury

Background: Mitochondrial dysfunction played a vital role in the pathogenesis of various diseases, including acute lung injury (ALI). However, few strategies targeting mitochondria were developed in treating ALI. Recently, we fabricated a porous Se@SiO2 nanoparticles (NPs) with antioxidant propertie...

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Veröffentlicht in:	International journal of nanomedicine 2020-01, Vol.15, p.2287-2302
Hauptverfasser:	Wang, Muyun, Wang, Kun, Deng, Guoying, Liu, Xijian, Wu, Xiaodong, Hu, Haiyang, Zhang, Yanbei, Gao, Wei, Li, Qiang
Format:	Artikel
Sprache:	eng
Schlagworte:	acute lung injury Alzheimer's disease anti-inflammation anti-oxidative injury Apoptosis Cell culture Cytotoxicity Data analysis Homeostasis Laboratory animals Lavage Life Sciences & Biomedicine Metabolism Mitochondria mitochondrial dysfunction Morphology Nanoparticles Nanoscience & Nanotechnology Original Research Oxidative stress Pathogenesis Pharmacology & Pharmacy Physiology porous se@sio2 nanoparticles Quantum dots Science & Technology Science & Technology - Other Topics Transmission electron microscopy
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