Promoted Antitumor Activity of Myricetin against Lung Carcinoma Via Nanoencapsulated Phospholipid Complex in Respirable Microparticles

Purpose Myricetin (MYR) flavonoid is well-recognized for its antioxidant, anti-inflammatory and anti-tumor potential. Introducing nanomedicine was the ultimate resort to solve the imperfections of this nutraceutical, namely solubility, stability and delivery issues. The study, thus, aims at developi...

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Veröffentlicht in:	Pharmaceutical research 2020-04, Vol.37 (4), p.82, Article 82
Hauptverfasser:	Nafee, Noha, Gaber, Dina M., Elzoghby, Ahmed O., Helmy, Maged W., Abdallah, Osama Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Administration, Inhalation Antineoplastic Agents - administration & dosage Antineoplastic Agents - metabolism Antineoplastic Agents - pharmacology Antioxidants Antitumor activity Biochemistry Bioflavonoids Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Cancer Carcinoma Cell Survival - drug effects Drug Carriers - chemistry Drug Compounding Drug Liberation Drying Flavones Flavonoids Flavonoids - administration & dosage Flavonoids - metabolism Flavonoids - pharmacology Functional foods Humans Inflammation Lung cancer Lung carcinoma Lung Neoplasms - drug therapy Medical Law Microparticles Nanoparticles Nanoparticles - chemistry Nanotechnology Particle Size Pharmacology/Toxicology Pharmacy Phospholipids Phospholipids - chemistry Physicochemical properties Research Paper Solubility Surface active agents Surface Properties Tissue Distribution
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