Peroxiredoxin 4 inhibits insulin-induced adipogenesis through regulation of ER stress in 3T3-L1 cells

Obesity was originally considered a disease endemic to developed countries but has since emerged as a global health problem. Obesity is characterized by abnormal or excessive lipid accumulation (World Health Organization, WHO) resulting from pre-adipocyte differentiation (adipogenesis). The endoplas...

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Veröffentlicht in:	Molecular and cellular biochemistry 2020-05, Vol.468 (1-2), p.97-109
Hauptverfasser:	Kim, Jae Yeop, Kim, Mi Hye, Lee, Hong Jun, Huh, Jae-Won, Lee, Sang-Rae, Lee, Hyun-Shik, Lee, Dong-Seok
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Accumulation Adipocytes Adipocytes - drug effects Adipocytes - enzymology Adipocytes - metabolism Adipogenesis Adipogenesis - drug effects Adipogenesis - genetics Animals Biochemistry Biomedical and Life Sciences Calcium - metabolism Cardiology Cholesterol Developed countries Differentiation Endoplasmic reticulum Endoplasmic Reticulum - metabolism Endoplasmic Reticulum Stress - drug effects Endoplasmic Reticulum Stress - genetics Gene expression Gene Expression Regulation - drug effects Gene Expression Regulation - genetics Global health Health aspects Insulin Insulin - pharmacology Life Sciences Lipid Metabolism - genetics Lipids Medical Biochemistry Metabolic disorders Mice Obesity Obesity - genetics Obesity - metabolism Oncology Peroxiredoxin Peroxiredoxins - genetics Peroxiredoxins - metabolism Proteins Reactive oxygen species Reactive Oxygen Species - metabolism Scavenging Type 2 diabetes
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