Antiarrhythmic agents based on diterpenoid alkaloid lappaconitine. Protonation of N-deacethyllappaconitine in methanol solutions

The data on antiarrhythmic drugs based on diterpene alkaloid lappaconitine are summarized. N -Deacetyllappaconitine is the main metabolite of allapinin and a potential antiarrhythmics for intravenous use. The basicity of two nitrogen atoms of this compound and the possibility of obtaining mono- and...

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Veröffentlicht in:	Russian chemical bulletin 2020-03, Vol.69 (3), p.567-571
Hauptverfasser:	Akhiyarov, A. A., Lobov, A. N., Ivanov, S. P., Spirikhin, L. V., Gabbasov, T. M., Tsyrlina, E. M., Valiev, N. V., Sadikov, A. Z., Sagdullaev, Sh. Sh, Yunusov, M. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Basicity Chemistry Chemistry and Materials Science Chemistry/Food Science Full Articles Hydrobromides Hydrochlorides Inorganic Chemistry Metabolites Nitrogen atoms NMR spectroscopy Organic Chemistry Protonation Titration
Online-Zugang:	Volltext
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