Anti‐MDA5‐associated dermatomyositis

Anti‐MDA5‐associated dermatomyositis (MDA5‐associated DM) is an uncommon presentation of idiopathic inflammatory myositis, typically amyopathic, associated with rapidly progressive, treatment refractory interstitial lung disease and poor prognosis, particularly in patients with concomitant rapidly p...

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Veröffentlicht in:Internal medicine journal 2020-04, Vol.50 (4), p.484-487
Hauptverfasser: Gupta, Rajiv, Kumar, Sunil, Gow, Peter, (Hsien‐Cheng) Chang, Leon, Yen, Linda
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container_issue 4
container_start_page 484
container_title Internal medicine journal
container_volume 50
creator Gupta, Rajiv
Kumar, Sunil
Gow, Peter
(Hsien‐Cheng) Chang, Leon
Yen, Linda
description Anti‐MDA5‐associated dermatomyositis (MDA5‐associated DM) is an uncommon presentation of idiopathic inflammatory myositis, typically amyopathic, associated with rapidly progressive, treatment refractory interstitial lung disease and poor prognosis, particularly in patients with concomitant rapidly progressive interstitial lung disease (RP‐ILD). We report two cases of MDA5‐associated DM with fatal outcome in one of the patients, despite ‘aggressive triple therapy’ for RP‐ILD.
doi_str_mv 10.1111/imj.14789
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subjects anti‐MDA5‐associated dermatomyositis
Autoantibodies
cyclosporine
Dermatomyositis
Dermatomyositis - complications
Dermatomyositis - diagnosis
Dermatomyositis - drug therapy
General & Internal Medicine
Humans
Inflammation
inflammatory myopathy
intravenous immunoglobulins
Life Sciences & Biomedicine
Lung diseases
Lung Diseases, Interstitial - diagnostic imaging
Lung Diseases, Interstitial - etiology
MDA5‐associated interstitial lung disease
Medicine, General & Internal
Myositis
Science & Technology
title Anti‐MDA5‐associated dermatomyositis
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