Molecular and Genetic Aspects of Helicobacter pylori Interaction with Cells of Gastric Mucosa
This paper considers current views on the classical determinants of Helicobacter pylori virulence, pathogenetic effects of phosphorylation, and the process of CagA translocation into gastric mucosa (GM) cells and characterizes surface membrane receptors of VacA binding to epithelial cells of the gas...
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| Veröffentlicht in: | Cytology and genetics 2020-03, Vol.54 (2), p.147-153 |
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| container_title | Cytology and genetics |
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| creator | Sukhan, D. S. Vernygorodskyi, S. V. Haidukov, N. V. Ludkevich, H. P. |
| description | This paper considers current views on the classical determinants of
Helicobacter pylori
virulence, pathogenetic effects of phosphorylation, and the process of CagA translocation into gastric mucosa (GM) cells and characterizes surface membrane receptors of VacA binding to epithelial cells of the gastric mucosa. The necessity of genetic typing of
Helicobacter pylori
to determine the potential virulence of a microorganism in order to predict the course of
H. pylori
-associated diseases and to select targeted therapy is substantiated. |
| doi_str_mv | 10.3103/S0095452720020139 |
| format | Article |
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Helicobacter pylori
virulence, pathogenetic effects of phosphorylation, and the process of CagA translocation into gastric mucosa (GM) cells and characterizes surface membrane receptors of VacA binding to epithelial cells of the gastric mucosa. The necessity of genetic typing of
Helicobacter pylori
to determine the potential virulence of a microorganism in order to predict the course of
H. pylori
-associated diseases and to select targeted therapy is substantiated.</description><identifier>ISSN: 0095-4527</identifier><identifier>EISSN: 1934-9440</identifier><identifier>DOI: 10.3103/S0095452720020139</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Biomedical and Life Sciences ; Biomedicine ; Epithelial cells ; Gastric mucosa ; Helicobacter pylori ; Human Genetics ; Phosphorylation ; Virulence</subject><ispartof>Cytology and genetics, 2020-03, Vol.54 (2), p.147-153</ispartof><rights>Allerton Press, Inc. 2020</rights><rights>Allerton Press, Inc. 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c316t-3c5894260f28aaa60f35a633e94641802e1236dfe2b8338e050da7efae048773</citedby><cites>FETCH-LOGICAL-c316t-3c5894260f28aaa60f35a633e94641802e1236dfe2b8338e050da7efae048773</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.3103/S0095452720020139$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.3103/S0095452720020139$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids></links><search><creatorcontrib>Sukhan, D. S.</creatorcontrib><creatorcontrib>Vernygorodskyi, S. V.</creatorcontrib><creatorcontrib>Haidukov, N. V.</creatorcontrib><creatorcontrib>Ludkevich, H. P.</creatorcontrib><title>Molecular and Genetic Aspects of Helicobacter pylori Interaction with Cells of Gastric Mucosa</title><title>Cytology and genetics</title><addtitle>Cytol. Genet</addtitle><description>This paper considers current views on the classical determinants of
Helicobacter pylori
virulence, pathogenetic effects of phosphorylation, and the process of CagA translocation into gastric mucosa (GM) cells and characterizes surface membrane receptors of VacA binding to epithelial cells of the gastric mucosa. The necessity of genetic typing of
Helicobacter pylori
to determine the potential virulence of a microorganism in order to predict the course of
H. pylori
-associated diseases and to select targeted therapy is substantiated.</description><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Epithelial cells</subject><subject>Gastric mucosa</subject><subject>Helicobacter pylori</subject><subject>Human Genetics</subject><subject>Phosphorylation</subject><subject>Virulence</subject><issn>0095-4527</issn><issn>1934-9440</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp1kEFLw0AQhRdRsFZ_gLcFz9HZnU2yOZaibaHFg71K2G4nmhKzcTdB-u_dtoIH8TTMvO-9gcfYrYB7FIAPLwBFqlKZSwAJAoszNhIFqqRQCs7Z6CAnB_2SXYWwA0gziThiryvXkB0a47lpt3xGLfW15ZPQke0DdxWfU1NbtzG2J8-7feN8zRdtXOKldi3_qvt3PqWmOdIzE3ofA1aDdcFcs4vKNIFufuaYrZ8e19N5snyeLaaTZWJRZH2CNtWFkhlUUhtj4sTUZIhUqEwJDZKExGxbkdxoRE2QwtbkVBkCpfMcx-zuFNt59zlQ6MudG3wbP5YSdS61kAVESpwo610Inqqy8_WH8ftSQHkosfxTYvTIkydEtn0j_5v8v-kbGghyZA</recordid><startdate>20200301</startdate><enddate>20200301</enddate><creator>Sukhan, D. S.</creator><creator>Vernygorodskyi, S. V.</creator><creator>Haidukov, N. V.</creator><creator>Ludkevich, H. P.</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20200301</creationdate><title>Molecular and Genetic Aspects of Helicobacter pylori Interaction with Cells of Gastric Mucosa</title><author>Sukhan, D. S. ; Vernygorodskyi, S. V. ; Haidukov, N. V. ; Ludkevich, H. P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c316t-3c5894260f28aaa60f35a633e94641802e1236dfe2b8338e050da7efae048773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Epithelial cells</topic><topic>Gastric mucosa</topic><topic>Helicobacter pylori</topic><topic>Human Genetics</topic><topic>Phosphorylation</topic><topic>Virulence</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sukhan, D. S.</creatorcontrib><creatorcontrib>Vernygorodskyi, S. V.</creatorcontrib><creatorcontrib>Haidukov, N. V.</creatorcontrib><creatorcontrib>Ludkevich, H. P.</creatorcontrib><collection>CrossRef</collection><jtitle>Cytology and genetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sukhan, D. S.</au><au>Vernygorodskyi, S. V.</au><au>Haidukov, N. V.</au><au>Ludkevich, H. P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Molecular and Genetic Aspects of Helicobacter pylori Interaction with Cells of Gastric Mucosa</atitle><jtitle>Cytology and genetics</jtitle><stitle>Cytol. Genet</stitle><date>2020-03-01</date><risdate>2020</risdate><volume>54</volume><issue>2</issue><spage>147</spage><epage>153</epage><pages>147-153</pages><issn>0095-4527</issn><eissn>1934-9440</eissn><abstract>This paper considers current views on the classical determinants of
Helicobacter pylori
virulence, pathogenetic effects of phosphorylation, and the process of CagA translocation into gastric mucosa (GM) cells and characterizes surface membrane receptors of VacA binding to epithelial cells of the gastric mucosa. The necessity of genetic typing of
Helicobacter pylori
to determine the potential virulence of a microorganism in order to predict the course of
H. pylori
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| ispartof | Cytology and genetics, 2020-03, Vol.54 (2), p.147-153 |
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| language | eng |
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| source | SpringerLink Journals - AutoHoldings |
| subjects | Biomedical and Life Sciences Biomedicine Epithelial cells Gastric mucosa Helicobacter pylori Human Genetics Phosphorylation Virulence |
| title | Molecular and Genetic Aspects of Helicobacter pylori Interaction with Cells of Gastric Mucosa |
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