PNPLA3 and TM6SF2, but Not MBOAT7, Are Associated with Steatosis and HBV Viral Persistence in Pakistani Population

Background: Hepatitis B infection has an intimate relationship with lipids. The role of lipid-related variants remains unknown in the risk of hepatitis B infection persistence and steatosis in the Pakistani population. Recently, three GWAS-based polymorphisms in the TM6SF2, PNPLA3, and MBOAT7 genes...

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Veröffentlicht in:	Jundishapur journal of microbiology 2020-01, Vol.13 (1), p.1-6
Hauptverfasser:	Jalil, Ismail, Arshad, Muhammad, Khan, Shahtaj, Dasti, Javid Iqbal
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Chronic infection Deoxyribonucleic acid DNA Fatty liver Genetic diversity Genotype & phenotype Genotyping Hepatitis Hepatitis B Immunization Infections Laboratories Lipids Liver cancer Liver diseases Patients Polymorphism Population Regression analysis Single-nucleotide polymorphism Steatosis Ultrasonic imaging
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