Inhibition of inflammatory mediator release from microglia can treat ischemic/hypoxic brain injury

Interleukin-1α and interleukin-1β aggravate neuronal injury by mediating the inflammatory reaction following ischemic/hypoxic brain injury. It remains unclear whether interleukin-1α and interleukin-1β are released by microglia or astrocytes. This study prepared hippocampal slices that were subsequen...

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Veröffentlicht in:	Neural regeneration research 2013-05, Vol.8 (15), p.1157-1168
Hauptverfasser:	Wang, Huaibo, Guo, Weitao, Liu, Hongliang, Zeng, Rong, Lu, Mingnan, Chen, Ziqiu, Xiao, Qixian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphate Apoptosis Cytokines Cytoplasm Dehydrogenases Glucose Hypoxia Investigations Ischemia Membranes Morphology Nervous system Traumatic brain injury Tumor necrosis factor-TNF
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