PAX8 expression in anaplastic thyroid carcinoma is less than those reported in early studies: a multi-institutional study of 182 cases using the monoclonal antibody MRQ-50

Anaplastic thyroid carcinoma (ATC) is an aggressive malignant tumor composed of undifferentiated thyroid follicular cells. Pathological diagnosis of ATC can be challenging as the tumor may show morphological overlap with other neoplasms with anaplastic morphology. Immunohistochemical demonstration o...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2020-03, Vol.476 (3), p.431-437
Hauptverfasser:	Lai, Wei-An, Hang, Jen-Fan, Liu, Chih-Yi, Bai, Yanhua, Liu, Zhiyan, Gu, Haiyan, Hong, SoonWon, Pyo, Ju Yeon, Jung, Chan Kwon, Kakudo, Kennichi, Bychkov, Andrey
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antibodies, Monoclonal Biomarkers, Tumor - analysis Diagnosis Female Histology Humans Immunohistochemistry Immunohistochemistry - methods Male Medicine Medicine & Public Health Middle Aged Monoclonal antibodies Morphology Neoplasia Neoplasms Original Article Pathology Pax8 protein PAX8 Transcription Factor - analysis PAX8 Transcription Factor - biosynthesis Thyroid Thyroid cancer Thyroid carcinoma Thyroid Carcinoma, Anaplastic - diagnosis Thyroid Neoplasms - diagnosis Tumors
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