Role of the treatment environment in the effects of aripiprazole on ethanol-induced behavioral sensitization and conditioned place preference in female mice

•Behavioral sensitization to ethanol (BSE) only occurred after a drug-free interval.•Repeated treatment with aripiprazole attenuated the expression of BSE.•The effects of aripiprazole on BSE did not depend on the treatment environment.•Aripiprazole prevented the reinstatement of ethanol-induced CPP....

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Veröffentlicht in:	Drug and alcohol dependence 2020-03, Vol.208, p.107856, Article 107856
Hauptverfasser:	Libarino-Santos, Matheus, de Santana Santos, Ana Catherine Gomes, Cata-Preta, Elisangela G., Barros-Santos, Thaísa, Nunes Brandão, Nina Rosa, Borges, Aurea Lorena Nunes, Santos-Baldaia, Renan, Hollais, André W., Baldaia, Marilia A., Berro, Laís F., Marinho, Eduardo A.V., Frussa-Filho, Roberto, Oliveira-Lima, Alexandre J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Drinking - drug therapy Alcohol Drinking - psychology Alcohol related disorders Alcohol use Alcohol-Related Disorders - drug therapy Alcohol-Related Disorders - psychology Alcoholism Animal models Animals Antipsychotics Aripiprazole Aripiprazole - pharmacology Behavior Behavior, Animal - drug effects Behavioral sensitization Cages Cocaine Conditioned place preference Conditioning, Classical - drug effects Disease Models, Animal Dopamine Dopamine Agonists - pharmacology Dopamine D2 receptors Drug abuse Efficacy Environment Environmental effects Ethanol Female Females Hostility Induced Mice Narcotics Place preference conditioning Reinstatement Rodents Sensitization Serotonin Serotonin receptors Serotonin S1 receptors Serotonin S2 receptors Substance abuse treatment
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