Synthesis of novel dimeric compounds containing triazole using click method and their selective antiproliferative and proapoptotic potential via mitochondrial apoptosis signaling

In this study, the main aim was synthesis of dimeric compounds, which contain lithocholic acid and a triazole structure to investigate the selective cellular and molecular antiproliferative and proapoptotic potential of these products in healthy embryonic fibroblast (MEF), cervix cancer (HeLa), and...

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Veröffentlicht in:Medicinal chemistry research 2020-04, Vol.29 (4), p.643-655
Hauptverfasser: Karabulut, H. R. Ferhat, Karatavuk, Ali Osman, Ozyildirim, Hasan, Doğanlar, Oğuzhan, Doğanlar, Zeynep Banu
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Sprache:eng
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