Sensitive RNase A detection and intracellular imaging using a natural compound-assisted tetrahedral DNA nanoprobe

We report an intracellular imaging and assay nanoplatform for RNase A using a DNA tetrahedron-based fluorescent probe as a substrate. Importantly, a natural compound was used as an RNase A activity stimulator to improve the sensitivity. This platform provides an alternative for the diagnosis and pro...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2020-03, Vol.56 (21), p.3229-3232
Hauptverfasser:	Tong, Chunyi, Hu, Yalei, Xie, Qian, Zhou, Ting, Fan, Jialong, Qin, Yan, Liu, Bin, Wang, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Products - chemistry DNA - chemistry Drug Evaluation, Preclinical Fluorescent Dyes - chemistry Fluorescent indicators Hep G2 Cells Humans Medical imaging Optical Imaging Ribonuclease, Pancreatic - analysis Ribonuclease, Pancreatic - metabolism Stimulators Substrates Tetrahedra
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!