Light at Night and Cancer Risk
Environmental lighting powerfully suppresses the physiologic release of melatonin, which typically peaks in the middle of the night. This decreased melatonin production has been hypothesized to increase the risk of cancer. Evidence from experimental studies supports a link between melatonin and tumo...
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Veröffentlicht in: | Photochemistry and photobiology 2004-04, Vol.79 (4), p.316-318 |
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creator | Schernhammer, Eva Schulmeister, Karl |
description | Environmental lighting powerfully suppresses the physiologic release of melatonin, which typically peaks in the middle of the night. This decreased melatonin production has been hypothesized to increase the risk of cancer. Evidence from experimental studies supports a link between melatonin and tumor growth. There is also fairly consistent indirect evidence from observational studies for an association between melatonin suppression, using night work as a surrogate, and breast cancer risk. |
doi_str_mv | 10.1562/SA-03-28.1 |
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source | MEDLINE; Wiley Online Library Journals Frontfile Complete; BioOne Complete |
subjects | Animals Cell Division Darkness Humans INVITED REVIEW Light - adverse effects Lighting - adverse effects Melatonin - biosynthesis Melatonin - deficiency Neoplasms - etiology Neoplasms - mortality Neoplasms - pathology Occupational Exposure - adverse effects Risk Assessment Risk Factors Time Factors Work Schedule Tolerance - physiology |
title | Light at Night and Cancer Risk |
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